Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.51 |
| ▸ | PPARA | Q07869 | 11/20 | 0.51 |
| ▸ | PPARD | Q03181 | 6/20 | 0.51 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6543100 | 0.92 | PPARG (0.53) | PPARGPPARAPPARDP2RY14TP53 | |
| SCHEMBL6544255 | 0.91 | PPARG (0.55) | PPARGPPARAPPARDCYSLTR2CYSLTR1 | |
| SCHEMBL6543540 | 0.90 | PPARA (0.49) | PPARGPPARAPPARDTP53 | |
| SCHEMBL6542995 | 0.87 | PPARG (0.53) | PPARGPPARAPPARD | |
| SCHEMBL6543548 | 0.87 | PPARG (0.55) | PPARGPPARAPPARDCYSLTR2CYSLTR1 | |
| SCHEMBL6544067 | 0.87 | PPARG (0.56) | PPARGPPARAPPARDP2RY14 | |
| SCHEMBL6542939 | 0.86 | PPARG (0.56) | PPARGPPARAPPARDTP53 | |
| SCHEMBL6543988 | 0.85 | PPARA (0.48) | PPARGPPARAPPARDTP53 | |
| SCHEMBL6542943 | 0.85 | PPARA (0.56) | PPARGPPARAPPARDTP53 | |
| SCHEMBL6544090 | 0.84 | PPARG (0.55) | PPARGPPARAPPARDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433786-A1 | Benzoxazole compound and pharmaceutical composition containing the compound | Kowa Company Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |
| US-6653334-B1 | Electively activate peroxisome proliferator activated receptors | KOWA CO., LTD. (JP) | 2003-11-25 | — | — | US | disclosed |