Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.49 |
| ▸ | PPARG | P37231 | 11/20 | 0.47 |
| ▸ | PPARD | Q03181 | 5/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6543988 | 0.95 | PPARA (0.48) | PPARAPPARGPPARDADRB3KDM4E | |
| SCHEMBL6544269 | 0.92 | ADRB3 (0.51) | PPARAPPARGPPARDADRB3KDM4E | |
| SCHEMBL6542989 | 0.90 | PPARG (0.51) | PPARAPPARGPPARDTP53 | |
| SCHEMBL6544142 | 0.90 | PPARG (0.51) | PPARAPPARGPPARDADRB3KDM4E | |
| SCHEMBL6544270 | 0.87 | PPARA (0.54) | PPARAPPARGPPARDADRB3KDM4E | |
| SCHEMBL6544132 | 0.85 | PPARA (0.54) | PPARAPPARGPPARDADRB3KDM4E | |
| SCHEMBL6543100 | 0.84 | PPARG (0.53) | PPARAPPARGPPARDADRB3KDM4E | |
| SCHEMBL6544023 | 0.84 | PPARA (0.54) | PPARAPPARGPPARDADRB3KDM4E | |
| SCHEMBL6544261 | 0.83 | PPARA (0.55) | PPARAPPARGPPARDADRB3KDM4E | |
| SCHEMBL6544255 | 0.83 | PPARG (0.55) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433786-A1 | Benzoxazole compound and pharmaceutical composition containing the compound | Kowa Company Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |
| US-6653334-B1 | Electively activate peroxisome proliferator activated receptors | KOWA CO., LTD. (JP) | 2003-11-25 | — | — | US | disclosed |