Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 6/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.39 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.39 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.39 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6543292 | 0.92 | ALDH1A1 (0.37) | NR1I2HTR2CPPARGMAPTKMT2A | |
| SCHEMBL6543286 | 0.92 | ALDH1A1 (0.37) | NR1I2HTR2CPPARGMAPTKMT2A | |
| SCHEMBL7233980 | 0.87 | TDP1 (0.47) | NR1I2HTR2CPPARGMAPTSLC22A6 | |
| SCHEMBL7233974 | 0.87 | TDP1 (0.47) | NR1I2HTR2CPPARGMAPTSLC22A6 | |
| SCHEMBL6238496 | 0.85 | TDP1 (0.51) | NR1I2HTR2CPPARGMAPTSLC22A6 | |
| SCHEMBL6238490 | 0.85 | TDP1 (0.51) | NR1I2HTR2CPPARGMAPTSLC22A6 | |
| SCHEMBL7867695 | 0.84 | NR1I2 (0.43) | NR1I2HTR2CPPARGMAPTSLC22A6 | |
| SCHEMBL7867701 | 0.84 | NR1I2 (0.43) | NR1I2HTR2CPPARGMAPTSLC22A6 | |
| SCHEMBL6760188 | 0.82 | NR1I2 (0.42) | NR1I2HTR2CPPARGMAPTSLC22A6 | |
| SCHEMBL6760190 | 0.82 | NR1I2 (0.42) | NR1I2HTR2CPPARGMAPTSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1333836-A4 | CEPHALOSPORIN ANTIBIOTICS AND PRODRUGS THEREOF | ESSENTIAL THERAPEUTICS INC (US) | 2004-07-07 | — | — | EP | disclosed |
| EP-1333836-A2 | CEPHALOSPORIN ANTIBIOTICS AND PRODRUGS THEREOF | Essential Therapeutics, Inc. (US) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002017854-A2 | CEPHALOSPORIN ANTIBIOTICS AND PRODRUGS THEREOF | ESSENTIAL THERAPEUTICS, INC. (US) | 2002-03-07 | — | — | WO | disclosed |