Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 5/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | APAF1 | O14727 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.40 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6760190 | 1.00 | NR1I2 (0.42) | NR1I2HTR2CMAPTPPARGALB | |
| SCHEMBL6243253 | 0.91 | ALDH1A1 (0.39) | NR1I2HTR2CMAPTPPARGALB | |
| SCHEMBL6238496 | 0.89 | TDP1 (0.51) | NR1I2HTR2CMAPTPPARGALB | |
| SCHEMBL6238490 | 0.89 | TDP1 (0.51) | NR1I2HTR2CMAPTPPARGALB | |
| SCHEMBL7867695 | 0.88 | NR1I2 (0.43) | NR1I2HTR2CMAPTPPARGALB | |
| SCHEMBL7867701 | 0.88 | NR1I2 (0.43) | NR1I2HTR2CMAPTPPARGALB | |
| SCHEMBL6233533 | 0.86 | KCNH2 (0.45) | NR1I2HTR2CMAPTPPARGALB | |
| SCHEMBL6238927 | 0.86 | KCNH2 (0.45) | NR1I2HTR2CMAPTPPARGALB | |
| SCHEMBL6543035 | 0.82 | NR1I2 (0.41) | NR1I2HTR2CMAPTPPARGALB | |
| SCHEMBL6541950 | 0.82 | ALDH1A1 (0.48) | NR1I2HTR2CMAPTPPARGPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723716-B1 | BACTERICIDE FOR STAPHYLOCOCCUS | ESSENTIAL THERAPEUTICS, INC. | 2004-04-20 | — | — | US | disclosed |