Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B7 | P16662 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TPH1 | P17752 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8439038 | 0.82 | UGT2B7 (0.59) | UGT2B7SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL14475276 | 0.82 | UGT2B7 (0.59) | UGT2B7SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL5075640 | 0.81 | KDM4E (0.52) | UGT2B7SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL5962501 | 0.81 | UGT2B7 (0.57) | UGT2B7SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL6034044 | 0.81 | UGT2B7 (0.57) | UGT2B7SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL31175221 | 0.80 | SLC6A2 (0.47) | SLC6A2SLC6A4CYP2D6AOC3KDM4E | |
| SCHEMBL2232118 | 0.80 | SLC6A2 (0.47) | SLC6A2SLC6A4CYP2D6AOC3KDM4E | |
| SCHEMBL19008845 | 0.77 | NR3C2 (0.41) | SLC6A2SLC6A4MEN1KMT2A | |
| SCHEMBL19737790 | 0.76 | UGT2B7 (0.52) | UGT2B7SLC6A2SLC6A4SLC6A3KCNH2 | |
| Hydrogen Peroxide SCHEMBL8096014 | 0.76 | UGT2B7 (0.72) | UGT2B7SLC6A2SLC6A4SLC6A3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1259475-A4 | TRANSITION METAL-CATALYZED PROCESS FOR ADDITION OF AMINES TO CARBON-CARBON DOUBLE BONDS | UNIV YALE (US) | 2004-08-18 | — | — | EP | disclosed |
| EP-1259475-A1 | TRANSITION METAL-CATALYZED PROCESS FOR ADDITION OF AMINES TO CARBON-CARBON DOUBLE BONDS | YALE UNIVERSITY (US) | 2002-11-27 | — | — | EP | disclosed |
| US-6384282-B2 | CATALYST IS REACTION PRODUCT OF GROUP 8 METAL AND LIGAND | YALE UNIVERSITY | 2002-05-07 | — | — | US | disclosed |
| US-20020016509-A1 | Transition metal-catalyzed process for addition of amines to carbon-carbon double bonds | YALE UNIVERSITY | 2002-02-07 | — | — | US | disclosed |
| WO-2001064620-A1 | TRANSITION METAL-CATALYZED PROCESS FOR ADDITION OF AMINES TO CARBON-CARBON DOUBLE BONDS | YALE UNIVERSITY (US) | 2001-09-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020016509-A1 | Transition metal-catalyzed process for addition of amines to carbon-carbon double bonds | COASY, CMA1, ATIC | UGT2B7 912/4885SLC6A2 358/4885SLC6A4 502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.