Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | CHKA | P35790 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31175221 | 0.87 | SLC6A2 (0.47) | SLC6A2SLC6A4MEN1ALDH1A1KMT2A | |
| SCHEMBL2232118 | 0.87 | SLC6A2 (0.47) | SLC6A2SLC6A4MEN1ALDH1A1KMT2A | |
| SCHEMBL13333786 | 0.85 | ALDH1A1 (0.45) | NR3C2S1PR1MEN1S1PR4ALDH1A1 | |
| SCHEMBL32689850 | 0.81 | NR3C2 (0.44) | NR3C2S1PR1MEN1S1PR4ALDH1A1 | |
| SCHEMBL10162929 | 0.81 | NR3C2 (0.44) | NR3C2S1PR1MEN1S1PR4ALDH1A1 | |
| SCHEMBL17830829 | 0.80 | SLC6A2 (0.50) | SLC6A2SLC6A4ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL17754486 | 0.79 | NR3C2 (0.43) | NR3C2SLC6A2SLC6A4S1PR1MEN1 | |
| SCHEMBL9659560 | 0.79 | NR3C2 (0.46) | NR3C2SLC6A2SLC6A4S1PR1MEN1 | |
| SCHEMBL7155149 | 0.78 | NR3C2 (0.56) | NR3C2S1PR1MEN1S1PR4ALDH1A1 | |
| SCHEMBL6543516 | 0.77 | UGT2B7 (0.53) | SLC6A2SLC6A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170275237-A1 | COMPOUNDS AND MIXTURES WITH ANTIDEGRADANT AND ANTIFATIGUE EFFICACY AND COMPOSITIONS INCLUDING SAID COMPOUNDS | EASTMAN CHEMICAL COMPANY (US) | 2017-09-28 | — | — | US | disclosed |
| US-20170275233-A1 | METHODS OF MAKING COMPOUNDS AND MIXTURES HAVING ANTIDEGRADANT AND ANTIFATIGUE EFFICACY | EASTMAN CHEMICAL COMPANY (US) | 2017-09-28 | — | — | US | disclosed |
| US-20170275238-A1 | METHODS OF MAKING COMPOUNDS AND MIXTURES HAVING ANTIDEGRADANT AND ANTIFATIGUE EFFICACY | EASTMAN CHEMICAL COMPANY (US) | 2017-09-28 | — | — | US | disclosed |
| US-20170275234-A1 | METHODS OF MAKING COMPOUNDS HAVING ANTIDEGRADANT AND ANTIFATIGUE EFFICACY | EASTMAN CHEMICAL COMPANY (US) | 2017-09-28 | — | — | US | disclosed |
| US-20170174615-A1 | COMPOUNDS WITH ANTIDEGRADANT AND ANTIFATIGUE EFFICACY AND COMPOSITIONS INCLUDING SAID COMPOUNDS | EASTMAN CHEMICAL COMPANY (US) | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170275237-A1 | COMPOUNDS AND MIXTURES WITH ANTIDEGRADANT AND ANTIFATIGUE EFFICACY AND COMPOSITIONS INCLUDING SAID COMPOUNDS | ACHE, CCNE2, CHRM1 | NR3C2 629/4885SLC6A2 2412/4885SLC6A4 1773/4885 |
| US-20170275234-A1 | METHODS OF MAKING COMPOUNDS HAVING ANTIDEGRADANT AND ANTIFATIGUE EFFICACY | ACHE, HNMT, PNMT | NR3C2 1701/4885SLC6A2 352/4885SLC6A4 405/4885 |
| US-20170275238-A1 | METHODS OF MAKING COMPOUNDS AND MIXTURES HAVING ANTIDEGRADANT AND ANTIFATIGUE EFFICACY | ACHE, BCHE, DDO | NR3C2 1959/4885SLC6A2 314/4885SLC6A4 370/4885 |
| US-20170174615-A1 | COMPOUNDS WITH ANTIDEGRADANT AND ANTIFATIGUE EFFICACY AND COMPOSITIONS INCLUDING SAID COMPOUNDS | ACHE, HDAC3, PON1 | NR3C2 730/4885SLC6A2 2543/4885SLC6A4 2037/4885 |
| US-20170275233-A1 | METHODS OF MAKING COMPOUNDS AND MIXTURES HAVING ANTIDEGRADANT AND ANTIFATIGUE EFFICACY | ACHE, DDO, BCHE | NR3C2 2433/4885SLC6A2 475/4885SLC6A4 422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.