SCHEMBL6544142

SCHEMBL6544142

CC(CCNCCCc1ccc(OC(C)(C)C(=O)O)cc1)Cc1nc2ccccc2o1

nearest known ligand 0.51

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PPARG P37231 14/20 0.51
PPARA Q07869 13/20 0.51
PPARD Q03181 3/20 0.51
ADRB3 P13945 3/20 0.45
KDM4E B2RXH2 1/20 0.43
MAPT P10636 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6544269 0.95 ADRB3 (0.51) PPARGPPARAPPARDADRB3KDM4E
SCHEMBL6544255 0.91 PPARG (0.55) PPARGPPARAPPARD
SCHEMBL6543540 0.90 PPARA (0.49) PPARGPPARAPPARDADRB3KDM4E
SCHEMBL2438034 0.89 PPARA (0.58) PPARGPPARAPPARDADRB3KDM4E
SCHEMBL6543988 0.89 PPARA (0.48) PPARGPPARAPPARDADRB3KDM4E
SCHEMBL6542915 0.88 PPARA (0.57) PPARGPPARAPPARDADRB3KDM4E
SCHEMBL6543548 0.87 PPARG (0.55) PPARGPPARAPPARD
SCHEMBL6544141 0.87 PPARA (0.56) PPARGPPARAPPARDADRB3KDM4E
SCHEMBL6543066 0.87 PPARA (0.57) PPARGPPARAPPARDADRB3KDM4E
SCHEMBL6544080 0.86 PPARA (0.57) PPARGPPARAPPARDADRB3KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1433786-A1 Benzoxazole compound and pharmaceutical composition containing the compound Kowa Company Ltd. (JP) 2004-06-30 EP disclosed
US-6653334-B1 Electively activate peroxisome proliferator activated receptors KOWA CO., LTD. (JP) 2003-11-25 US disclosed