Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.54 |
| ▸ | PPARA | Q07869 | 13/20 | 0.54 |
| ▸ | PPARD | Q03181 | 9/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6544107 | 0.91 | PPARG (0.53) | PPARGPPARAPPARDP2RY14CYP4F2 | |
| SCHEMBL6543207 | 0.91 | PPARA (0.44) | PPARGPPARAPPARDMAPTP2RY14 | |
| SCHEMBL6544235 | 0.90 | PPARA (0.51) | PPARGPPARAPPARDKDM4EMAPT | |
| SCHEMBL6543451 | 0.85 | PPARG (0.52) | PPARGPPARAPPARDKDM4EMAPT | |
| SCHEMBL6543077 | 0.79 | PPARG (0.60) | PPARGPPARAPPARDKDM4EMAPT | |
| SCHEMBL6544109 | 0.77 | PPARG (0.59) | PPARGPPARAPPARDKDM4EMAPT | |
| SCHEMBL2436469 | 0.77 | PPARG (0.63) | PPARGPPARAPPARDP2RY14CYP4F2 | |
| SCHEMBL6543898 | 0.76 | PPARG (0.58) | PPARGPPARAPPARDKDM4EMAPT | |
| SCHEMBL6544252 | 0.76 | PPARG (0.62) | PPARGPPARAPPARDMAPTCYP4F2 | |
| SCHEMBL6543114 | 0.76 | PPARG (0.57) | PPARGPPARAPPARDKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433786-A1 | Benzoxazole compound and pharmaceutical composition containing the compound | Kowa Company Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |
| US-6653334-B1 | Electively activate peroxisome proliferator activated receptors | KOWA CO., LTD. (JP) | 2003-11-25 | — | — | US | disclosed |