Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 13/20 | 0.51 |
| ▸ | PPARG | P37231 | 12/20 | 0.51 |
| ▸ | PPARD | Q03181 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | FABP2 | P12104 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6543451 | 0.95 | PPARG (0.52) | PPARAPPARGPPARDKDM4EMAPT | |
| SCHEMBL6543607 | 0.90 | PPARG (0.54) | PPARAPPARGPPARDKDM4EMAPT | |
| SCHEMBL6544107 | 0.83 | PPARG (0.53) | PPARAPPARGPPARDALDH1A1 | |
| SCHEMBL6543207 | 0.81 | PPARA (0.44) | PPARAPPARGPPARDMAPTALDH1A1 | |
| SCHEMBL1010861 | 0.79 | PPARA (0.58) | PPARAPPARGPPARDKDM4EMAPT | |
| SCHEMBL6543036 | 0.78 | PPARA (0.57) | PPARAPPARGPPARDKDM4EMAPT | |
| SCHEMBL6544080 | 0.76 | PPARA (0.57) | PPARAPPARGPPARDKDM4EMAPT | |
| SCHEMBL6543171 | 0.75 | PPARA (0.56) | PPARAPPARGPPARDKDM4EMAPT | |
| SCHEMBL2438034 | 0.74 | PPARA (0.58) | PPARAPPARGPPARDKDM4EMAPT | |
| SCHEMBL6544125 | 0.74 | PPARA (0.53) | PPARAPPARGPPARDKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433786-A1 | Benzoxazole compound and pharmaceutical composition containing the compound | Kowa Company Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |
| US-6653334-B1 | Electively activate peroxisome proliferator activated receptors | KOWA CO., LTD. (JP) | 2003-11-25 | — | — | US | disclosed |