SCHEMBL6543972

SCHEMBL6543972

Cc1cccc2ccc3cccc(N)c3c12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CD44 P16070 1/20 0.50
CYP3A4 P08684 5/20 0.46
TDP1 Q9NUW8 3/20 0.46
ALDH1A1 P00352 7/20 0.45
HPGD P15428 5/20 0.45
HSD17B10 Q99714 5/20 0.45
TSHR P16473 4/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
PIK3CA P42336 1/20 0.44
CYP1A2 P05177 5/20 0.43
CYP1A1 P04798 1/20 0.43
CYP1B1 Q16678 1/20 0.43
TYMS P04818 1/20 0.43
JAK2 O60674 1/20 0.42
RPS6KA3 P51812 1/20 0.42
MELK Q14680 1/20 0.42
STK24 Q9Y6E0 1/20 0.42
CYP2A6 P11509 2/20 0.39
KEAP1 Q14145 1/20 0.39
GLO1 Q04760 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31484742 0.91 CD44 (0.54) CD44CYP3A4TDP1ALDH1A1HPGD
SCHEMBL4083590 0.91 CD44 (0.54) CD44CYP3A4TDP1ALDH1A1HPGD
Hydrochloric Acid SCHEMBL28970550 0.88 CYP3A4 (0.54) CD44CYP3A4TDP1ALDH1A1HPGD
SCHEMBL4647758 0.85 CYP1A2 (0.59) CYP3A4TDP1ALDH1A1HPGDHSD17B10
SCHEMBL14742902 0.85 ALDH1A1 (0.59) CYP3A4TDP1ALDH1A1HPGDHSD17B10
O-Tolylamine SCHEMBL28911426 0.82 CYP3A4 (0.65) CD44CYP3A4TDP1ALDH1A1HPGD
SCHEMBL2799285 0.80 CYP3A4 (0.48) CD44CYP3A4TDP1ALDH1A1HPGD
SCHEMBL6185564 0.80 CD44 (0.54) CD44CYP3A4TDP1ALDH1A1HPGD
SCHEMBL27718656 0.80 CD44 (0.54) CD44CYP3A4TDP1ALDH1A1HPGD
SCHEMBL17065502 0.77 ALDH1A1 (0.50) CD44CYP3A4TDP1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040186261-A1 Rheological adjuncts, method for production and use thereof BASF COATINGS AKTIENGESELLSCHAFT (DE) 2004-09-23 US disclosed
EP-1417268-A1 RHEOLOGICAL ADJUNCTS, METHOD FOR PRODUCTION AND USE THEREOF BASF Coatings Aktiengesellschaft (DE) 2004-05-12 EP disclosed
WO-2003014233-A1 RHEOLOGICAL ADJUNCTS, METHOD FOR PRODUCTION AND USE THEREOF BASF COATINGS AG (DE) 2003-02-20 WO disclosed