Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD44 | P16070 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 6/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.45 |
| ▸ | MELK | Q14680 | 1/20 | 0.45 |
| ▸ | STK24 | Q9Y6E0 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31484742 | 1.00 | CD44 (0.54) | CD44CYP3A4TDP1TSHRPIK3CA | |
| Hydrochloric Acid SCHEMBL28970550 | 0.98 | CYP3A4 (0.54) | CD44CYP3A4TDP1TSHRPIK3CA | |
| SCHEMBL6543972 | 0.91 | CD44 (0.50) | CD44CYP3A4TDP1TSHRPIK3CA | |
| O-Tolylamine SCHEMBL28911426 | 0.86 | CYP3A4 (0.65) | CD44CYP3A4TDP1TSHRPIK3CA | |
| SCHEMBL29353343 | 0.81 | ALDH1A1 (0.53) | CYP3A4TDP1TSHRCYP1A2ALDH1A1 | |
| SCHEMBL29349435 | 0.81 | JAK2 (0.54) | CD44CYP3A4TDP1TSHRPIK3CA | |
| SCHEMBL588459 | 0.81 | ALDH1A1 (0.53) | CYP3A4TDP1TSHRCYP1A2ALDH1A1 | |
| SCHEMBL65699 | 0.81 | JAK2 (0.54) | CD44CYP3A4TDP1TSHRPIK3CA | |
| SCHEMBL6185564 | 0.79 | CD44 (0.54) | CD44CYP3A4TDP1TSHRPIK3CA | |
| SCHEMBL2799285 | 0.79 | CYP3A4 (0.48) | CD44CYP3A4TDP1TSHRPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12083498-B2 | Chromatographic materials for the separation of unsaturated molecules | WATERS TECHNOLOGIES CORPORATION (US) | 2024-09-10 | — | — | US | disclosed |
| CN-111644164-B | Chromatographic material for separating unsaturated molecules | 沃特世科技公司 | 2024-03-08 | — | — | CN | disclosed |
| US-20230212170-A1 | INHIBITORS OF KRAS G12C PROTEIN AND USES THEREOF | ANTENGENE DISCOVERY LIMITED (CN) | 2023-07-06 | — | — | US | disclosed |
| US-20230212170-A1 | INHIBITORS OF KRAS G12C PROTEIN AND USES THEREOF | ANTENGENE DISCOVERY LIMITED (CN) | 2023-07-06 | — | — | US | disclosed |
| US-20230212170-A1 | INHIBITORS OF KRAS G12C PROTEIN AND USES THEREOF | ANTENGENE DISCOVERY LIMITED (CN) | 2023-07-06 | — | — | US | disclosed |
| CN-112538084-B | Novel KRAS G12C protein inhibitor and preparation method and application thereof | 信达生物制药(苏州)有限公司 | 2023-06-20 | — | — | CN | disclosed |
| US-20230151133-A1 | COMPOSITION COMPRISING STYRENE ISOBUTYLENE BLOCK COPOLYMER AND ETHYLENICALLY UNSATURATED MONOMER | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2023-05-18 | — | — | US | disclosed |
| EP-4161934-A1 | INHIBITORS OF KRAS G12C PROTEIN AND USES THEREOF | ANTENGENE DISCOVERY LIMITED (CN) | 2023-04-12 | — | — | EP | disclosed |
| CN-115836072-A | Inhibitors of KRAS G12C protein and uses thereof | 上海德琪医药科技有限公司 | 2023-03-21 | — | — | CN | disclosed |
| EP-3710439-B1 | KRAS G12C INHIBITORS | MIRATI THERAPEUTICS INC (US) | 2023-02-15 | — | — | EP | disclosed |
| WO-2015134317-A1 | CHROMOTOGRAPHIC MATERIALS FOR THE SEPARATION OF UNSATURATED MOLECULES | WATERS TECHNOLOGIES CORPORATION (US) | 2015-09-11 | — | — | WO | disclosed |
| US-20140319057-A1 | CHROMATOGRAPHIC MATERIALS FOR THE SEPARATION OF UNSATURATED MOLECULES | WATERS TECHNOLOGIES CORPORATION (US) | 2014-10-30 | — | — | US | disclosed |
| US-8585780-B2 | Dyes and blends for shading during laundry | BASF SE (DE) | 2013-11-19 | — | — | US | disclosed |
| CN-1863784-B | 2-naphthylimino-1,3-thiazine derivative | SHIONOGI & CO | 2010-11-17 | — | — | CN | disclosed |
| US-7482339-B2 | 2-Naphthylimino-1,3-thiazine derivative | SHIONOGI AND CO., LTD. (JP) | 2009-01-27 | — | — | US | disclosed |
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| US-20060281738-A1 | 2-Naphthylimino-1,3-thiazine derivative | SHIONOGI AND CO., LTD. (JP) | 2006-12-14 | — | — | US | disclosed |
| CN-1863784-A | 2-naphthylimino-1,3-thiazine derivative | SHIONOGI & CO (JP) | 2006-11-15 | — | — | CN | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |
| EP-1659117-A1 | 2-NAPHTHYLIMINO-1,3-THIAZINE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2006-05-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060281738-A1 | 2-Naphthylimino-1,3-thiazine derivative | NPM1, OXTR, CYP2S1 | CD44 4738/4885CYP3A4 95/4885TDP1 3815/4885 |
| US-20230212170-A1 | INHIBITORS OF KRAS G12C PROTEIN AND USES THEREOF | KRAS, NRAS, HRAS | CD44 4027/4885CYP3A4 4611/4885TDP1 3527/4885 |
| US-12083498-B2 | Chromatographic materials for the separation of unsaturated molecules | C9, EPHX2, ALOX5 | CD44 926/4885CYP3A4 511/4885TDP1 4724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.