Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 14/20 | 0.47 |
| ▸ | PPARG | P37231 | 13/20 | 0.47 |
| ▸ | PPARD | Q03181 | 3/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6542994 | 0.93 | PPARA (0.47) | PPARAPPARGPPARDADRB3MAPT | |
| SCHEMBL6544120 | 0.86 | PPARA (0.47) | PPARAPPARGPPARD | |
| SCHEMBL6544135 | 0.84 | ADRB3 (0.56) | PPARAPPARGPPARDADRB3MAPT | |
| SCHEMBL6543036 | 0.79 | PPARA (0.57) | PPARAPPARGPPARDADRB3MAPT | |
| SCHEMBL6544269 | 0.78 | ADRB3 (0.51) | PPARAPPARGPPARDADRB3MAPT | |
| SCHEMBL1009876 | 0.78 | ADRB3 (0.56) | PPARAPPARGPPARDADRB3MAPT | |
| SCHEMBL6544080 | 0.77 | PPARA (0.57) | PPARAPPARGPPARDADRB3MAPT | |
| SCHEMBL6543126 | 0.76 | PPARA (0.50) | PPARAPPARGPPARDADRB3MAPT | |
| SCHEMBL6543171 | 0.76 | PPARA (0.56) | PPARAPPARGPPARDADRB3MAPT | |
| SCHEMBL1010866 | 0.75 | ADRB3 (0.52) | PPARAPPARGPPARDADRB3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433786-A1 | Benzoxazole compound and pharmaceutical composition containing the compound | Kowa Company Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |
| US-6653334-B1 | Electively activate peroxisome proliferator activated receptors | KOWA CO., LTD. (JP) | 2003-11-25 | — | — | US | disclosed |