Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 3/20 | 0.56 |
| ▸ | PPARA | Q07869 | 13/20 | 0.51 |
| ▸ | PPARG | P37231 | 12/20 | 0.51 |
| ▸ | PPARD | Q03181 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | FABP2 | P12104 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6543126 | 0.92 | PPARA (0.50) | ADRB3PPARAPPARGPPARDKDM4E | |
| SCHEMBL6543944 | 0.90 | PPARG (0.54) | ADRB3PPARAPPARGPPARDKDM4E | |
| SCHEMBL6543501 | 0.85 | ADRB3 (0.39) | ADRB3PPARAPPARGPPARDKDM4E | |
| SCHEMBL6544050 | 0.85 | PPARG (0.56) | ADRB3PPARAPPARGPPARDKDM4E | |
| SCHEMBL6543121 | 0.84 | PPARG (0.51) | ADRB3PPARAPPARGPPARDALDH1A1 | |
| SCHEMBL6544065 | 0.84 | PPARA (0.47) | ADRB3PPARAPPARGPPARDKDM4E | |
| SCHEMBL6543036 | 0.84 | PPARA (0.57) | ADRB3PPARAPPARGPPARDKDM4E | |
| SCHEMBL1009876 | 0.83 | ADRB3 (0.56) | ADRB3PPARAPPARGPPARDKDM4E | |
| SCHEMBL6544269 | 0.83 | ADRB3 (0.51) | ADRB3PPARAPPARGPPARDKDM4E | |
| SCHEMBL6543074 | 0.82 | PPARG (0.39) | ADRB3PPARAPPARGPPARDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433786-A1 | Benzoxazole compound and pharmaceutical composition containing the compound | Kowa Company Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |
| US-6653334-B1 | Electively activate peroxisome proliferator activated receptors | KOWA CO., LTD. (JP) | 2003-11-25 | — | — | US | disclosed |