SCHEMBL6544102

SCHEMBL6544102

CC(CCCNCCc1cccc(OC(C)(C)C(=O)OC(C)(C)C)c1)Cc1nc2ccccc2o1

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 11/20 0.44
PPARG P37231 10/20 0.44
PPARD Q03181 6/20 0.44
P2RY14 Q15391 2/20 0.36
TP53 P04637 1/20 0.34
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6542995 0.91 PPARG (0.53) PPARAPPARGPPARDMAPT
SCHEMBL6543548 0.88 PPARG (0.55) PPARAPPARGPPARD
SCHEMBL6543100 0.86 PPARG (0.53) PPARAPPARGPPARDP2RY14TP53
SCHEMBL6544255 0.85 PPARG (0.55) PPARAPPARGPPARD
SCHEMBL6544109 0.80 PPARG (0.59) PPARAPPARGPPARDTP53MAPT
SCHEMBL6543898 0.79 PPARG (0.58) PPARAPPARGPPARDTP53MAPT
SCHEMBL6542989 0.79 PPARG (0.51) PPARAPPARGPPARDP2RY14TP53
SCHEMBL6543077 0.79 PPARG (0.60) PPARAPPARGPPARDP2RY14MAPT
SCHEMBL6543114 0.79 PPARG (0.57) PPARAPPARGPPARDMAPT
SCHEMBL6544098 0.78 PPARG (0.61) PPARAPPARGPPARDTP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1433786-A1 Benzoxazole compound and pharmaceutical composition containing the compound Kowa Company Ltd. (JP) 2004-06-30 EP disclosed