Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6545010 | 0.83 | ALDH1A1 (0.43) | ALDH1A1NPSR1TSHRGAA | |
| SCHEMBL3856521 | 0.81 | ALDH1A1 (0.49) | ALDH1A1NPSR1TSHRL3MBTL1THRB | |
| SCHEMBL4371216 | 0.81 | ALDH1A1 (0.49) | ALDH1A1NPSR1TSHRL3MBTL1THRB | |
| SCHEMBL13660805 | 0.80 | ALDH1A1 (0.55) | ALDH1A1NPSR1TSHRL3MBTL1THRB | |
| SCHEMBL3455285 | 0.80 | ALDH1A1 (0.47) | ALDH1A1NPSR1TSHRL3MBTL1THRB | |
| SCHEMBL7136670 | 0.80 | ALDH1A1 (0.47) | ALDH1A1NPSR1TSHRL3MBTL1THRB | |
| SCHEMBL30436282 | 0.78 | ALDH1A1 (0.52) | ALDH1A1NPSR1TSHRL3MBTL1THRB | |
| SCHEMBL31618367 | 0.76 | ALDH1A1 (0.43) | ALDH1A1NPSR1TSHRL3MBTL1THRB | |
| SCHEMBL6544816 | 0.75 | EPHX1 (0.38) | ALDH1A1NPSR1KDM4EMEN1GAA | |
| SCHEMBL660922 | 0.73 | ALDH1A1 (0.54) | ALDH1A1NPSR1TSHRL3MBTL1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373186-A1 | A PROCESS FOR THE PREPARATION OF CYCLIC AMINO ACIDS | Solchem Italiana S.p.A (IT) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002074727-A1 | A PROCESS FOR THE PREPARATION OF CYCLIC AMINO ACIDS | SOLCHEM ITALIANA S.P.A. (IT) | 2002-09-26 | — | — | WO | disclosed |