SCHEMBL6545010

SCHEMBL6545010

C=CCOC(=O)C(C=NO)C1CCCCC1

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
GAA P10253 1/20 0.43
NPSR1 Q6W5P4 1/20 0.39
CASP1 P29466 1/20 0.37
NPC1 O15118 2/20 0.35
MAPT P10636 1/20 0.35
RAB9A P51151 1/20 0.35
TSHR P16473 2/20 0.32
EPHX1 P07099 1/20 0.31
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6544317 0.83 ALDH1A1 (0.46) ALDH1A1GAANPSR1TSHR
SCHEMBL6545168 0.82 ALDH1A1 (0.46) ALDH1A1GAANPSR1CASP1NPC1
SCHEMBL1234256 0.75 ALDH1A1 (0.48) ALDH1A1GAANPSR1CASP1NPC1
SCHEMBL6544816 0.74 EPHX1 (0.38) ALDH1A1GAANPSR1NPC1MAPT
SCHEMBL23340705 0.73 ALDH1A1 (0.47) ALDH1A1GAANPSR1CASP1NPC1
SCHEMBL3917383 0.73 ALDH1A1 (0.47) ALDH1A1GAANPSR1CASP1NPC1
SCHEMBL296011 0.73 ALDH1A1 (0.47) ALDH1A1GAANPSR1CASP1NPC1
SCHEMBL27573216 0.73 ALDH1A1 (0.47) ALDH1A1GAANPSR1CASP1NPC1
SCHEMBL11371838 0.73 ALDH1A1 (0.36) ALDH1A1GAANPSR1CASP1MAPT
SCHEMBL6870669 0.73 ALDH1A1 (0.45) ALDH1A1GAANPSR1CASP1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1373186-A1 A PROCESS FOR THE PREPARATION OF CYCLIC AMINO ACIDS Solchem Italiana S.p.A (IT) 2004-01-02 EP disclosed
WO-2002074727-A1 A PROCESS FOR THE PREPARATION OF CYCLIC AMINO ACIDS SOLCHEM ITALIANA S.P.A. (IT) 2002-09-26 WO disclosed