Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 6/20 | 0.33 |
| ▸ | CPT1A | P50416 | 3/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL6544753 | 0.89 | F2R (0.57) | F2RMAPTKDM4ENPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6545022 | 0.89 | F2R (0.56) | F2RMAPTKDM4ENPC1RAB9A | |
| SCHEMBL1731603 | 0.80 | F2R (0.59) | F2RCPT1A | |
| Bromide SCHEMBL5488808 | 0.79 | F2R (0.59) | F2RCPT1A | |
| Trifluoroacetic Acid SCHEMBL6544998 | 0.79 | F2R (0.45) | F2RMAPTKDM4ENPC1RAB9A | |
| SCHEMBL1732776 | 0.78 | F2R (0.51) | F2RMAPTKDM4ENPC1RAB9A | |
| Bromide SCHEMBL5483274 | 0.77 | F2R (0.52) | F2RMAPTKDM4ENPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL1729235 | 0.77 | F2R (0.53) | F2R | |
| Bromide SCHEMBL6544820 | 0.75 | KDM4E (0.34) | F2RMAPTKDM4ENPC1RAB9A | |
| Hydrochloric Acid SCHEMBL5483140 | 0.75 | F2R (0.56) | F2RRORCALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1391451-A1 | 2-IMINOPYRROLIDINE DERIVATES | Eisai Co., Ltd. (JP) | 2004-02-25 | — | — | EP | disclosed |