SCHEMBL6544382

SCHEMBL6544382

CC(C(=O)O)N(C)N1CCCCC1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 5/20 0.34
CHRM4 P08173 5/20 0.34
CHRM5 P08912 5/20 0.34
CHRM1 P11229 5/20 0.34
CHRM3 P20309 5/20 0.34
DPP7 Q9UHL4 1/20 0.32
GAA P10253 1/20 0.31
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19465584 0.72
SCHEMBL2519318 0.72 F2 (0.32) DPP7GAA
SCHEMBL2519317 0.72 F2 (0.32) DPP7GAA
SCHEMBL6632132 0.70 ALDH1A1 (0.36) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL7410519 0.69 DPP7 (0.33) DPP7
SCHEMBL17010753 0.68 ALDH1A1 (0.36) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL94069 0.64 DPP7 (0.45) DPP7GAA
SCHEMBL10939615 0.64 DPP7 (0.45) DPP7GAA
SCHEMBL4592349 0.64 CHRM2 (0.37) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL4938808 0.64 DPP7 (0.45) DPP7GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0931792-B1 Depsipeptides containing non-natural amino acids NISSHIN SEIFUN GROUP INC (JP) 2004-01-07 EP claimed