Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6544471 | 1.00 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2GAAMAPTLMNA | |
| SCHEMBL6544462 | 0.89 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2GAAMAPTLMNA | |
| SCHEMBL6544465 | 0.89 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2GAAMAPTLMNA | |
| SCHEMBL6545182 | 0.87 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2GAAMAPTLMNA | |
| SCHEMBL6545179 | 0.87 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2GAAMAPTLMNA | |
| SCHEMBL6544298 | 0.85 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2GAAMAPTLMNA | |
| SCHEMBL6544299 | 0.85 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2GAAMAPTLMNA | |
| SCHEMBL6544461 | 0.83 | GAA (0.52) | ALDH1A1SMN1; SMN2GAAMAPTLMNA | |
| SCHEMBL6544464 | 0.83 | GAA (0.52) | ALDH1A1SMN1; SMN2GAAMAPTLMNA | |
| SCHEMBL6544284 | 0.78 | GAA (0.63) | ALDH1A1SMN1; SMN2GAAMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140819-B1 | ALFA-SULFENIMINO ACID DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-01-02 | — | — | EP | disclosed |
| US-6479550-B1 | α-sulfenimino acid derivatives | SYNGENTA CROP PROTECTION, INC. | 2002-11-12 | — | — | US | disclosed |
| EP-1140819-A1 | ALFA-SULFENIMINO ACID DERIVATIVES | Syngenta Participations AG (CH) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000042007-A1 | ALFA-SULFENIMINO ACID DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-07-20 | — | — | WO | disclosed |