Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GJB2 | P29033 | 2/20 | 0.43 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.41 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.41 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.41 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.41 |
| ▸ | TACR2 | P21452 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | CDC25B | P30305 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18636425 | 0.88 | PDE2A (0.48) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL16756817 | 0.88 | PDE2A (0.48) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL16756820 | 0.88 | PDE2A (0.48) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL17039975 | 0.88 | PDE2A (0.48) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL29711813 | 0.88 | PDE2A (0.48) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL24371602 | 0.88 | PDE2A (0.48) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL4615596 | 0.86 | HTR1A (0.48) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL29410621 | 0.86 | HTR1A (0.48) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL16389629 | 0.85 | SLC6A2 (0.45) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL264661 | 0.84 | SSTR1 (0.52) | GJB2SSTR1SSTR2SSTR4SSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373288-A1 | PROCESS FOR THE PREPARATION OF 2'-HALO-BETA-L-ARABINOFURANOSYL NUCLEOSIDES | Triangle Pharmaceuticals Inc. (US) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002079213-A1 | PROCESS FOR THE PREPARATION OF 2'-HALO-$G(B)-L-ARABINOFURANOSYL NUCLEOSIDES | TRIANGLE PHARMACEUTICALS, INC. (US) | 2002-10-10 | — | — | WO | disclosed |