Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Acetate SCHEMBL3776197 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10TSHRPOLB | |
| Ethyl Acetate SCHEMBL130336 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10TSHRPOLB | |
| Ethyl Acetate SCHEMBL15194119 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10TSHRPOLB | |
| Ethyl Acetate SCHEMBL16332300 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10TSHRPOLB | |
| Ethyl Acetate SCHEMBL3909115 | 0.98 | ALDH1A1 (0.61) | ALDH1A1LMNAHSD17B10TSHRPOLB | |
| Ethyl Acetate SCHEMBL1057423 | 0.98 | ALDH1A1 (0.61) | ALDH1A1LMNAHSD17B10TSHRPOLB | |
| Cyclohexane SCHEMBL11112885 | 0.98 | ALDH1A1 (0.61) | ALDH1A1LMNAHSD17B10TSHRPOLB | |
| Ethyl Acetate SCHEMBL3423313 | 0.98 | ALDH1A1 (0.61) | ALDH1A1LMNAHSD17B10TSHRPOLB | |
| Ethyl Acetate SCHEMBL1873691 | 0.98 | ALDH1A1 (0.61) | ALDH1A1LMNAHSD17B10TSHRPOLB | |
| Ethyl Acetate SCHEMBL28106135 | 0.98 | ALDH1A1 (0.61) | ALDH1A1LMNAHSD17B10TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1022272-B1 | SUBSTITUTED FUSED HETEROCYCLIC COMPOUNDS | SANKYO CO (JP) | 2004-05-26 | — | — | EP | disclosed |
| US-6432993-B1 | BENZIMIDAZOLE OR IMIDAZO(4,5-B)PYRIDINE DERIVATES; IMMUNOMODULATORS; ALDOSE REDUCTASE AND LIPOXYGENASE INHIBITORS; DIABETES; PREVENTS LIPID PEROXIDATION; ANTILIPEMIC, HYPOTENSIVE AGENTS | SANKYO COMPANY, LIMITED (JP) | 2002-08-13 | — | — | US | disclosed |
| EP-1022272-A1 | SUBSTITUTED FUSED HETEROCYCLIC COMPOUNDS | Sankyo Company Limited (JP) | 2000-07-26 | — | — | EP | disclosed |