Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Acetate SCHEMBL3776197 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10TSHRPOLB | |
| Ethyl Acetate SCHEMBL15194119 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10TSHRPOLB | |
| Ethyl Acetate SCHEMBL16332300 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10TSHRPOLB | |
| Ethyl Acetate SCHEMBL6544884 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10TSHRPOLB | |
| Ethyl Acetate SCHEMBL3909115 | 0.98 | ALDH1A1 (0.61) | ALDH1A1LMNAHSD17B10TSHRPOLB | |
| Ethyl Acetate SCHEMBL1057423 | 0.98 | ALDH1A1 (0.61) | ALDH1A1LMNAHSD17B10TSHRPOLB | |
| Cyclohexane SCHEMBL11112885 | 0.98 | ALDH1A1 (0.61) | ALDH1A1LMNAHSD17B10TSHRPOLB | |
| Ethyl Acetate SCHEMBL3423313 | 0.98 | ALDH1A1 (0.61) | ALDH1A1LMNAHSD17B10TSHRPOLB | |
| Ethyl Acetate SCHEMBL1873691 | 0.98 | ALDH1A1 (0.61) | ALDH1A1LMNAHSD17B10TSHRPOLB | |
| Ethyl Acetate SCHEMBL28106135 | 0.98 | ALDH1A1 (0.61) | ALDH1A1LMNAHSD17B10TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1583 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118894777-A | Caffeic acid crystal form and preparation method thereof | 德州德药制药有限公司 | 2024-11-05 | — | — | CN | claimed |
| CN-117352658-A | Double-ion battery in-situ electropolymerization positive electrode, battery and preparation method and application thereof | 深圳先进技术研究院 | 2024-01-05 | — | — | CN | claimed |
| CN-115197075-A | Preparation method of efavirenz key intermediate | 盐城迪赛诺制药有限公司 | 2022-10-18 | — | — | CN | claimed |
| CN-112851623-B | Method for preparing epsilon-caprolactone, 6-hydroxycaproic acid and ester thereof by using tetrahydrofurfuryl acetic acid and ester thereof | 中国科学院兰州化学物理研究所 | 2022-04-08 | — | — | CN | claimed |
| CN-113968791-A | Preparation method of efavirenz key intermediate | 盐城迪赛诺制药有限公司 | 2022-01-25 | — | — | CN | claimed |
| CN-112851623-A | Method for preparing epsilon-caprolactone, 6-hydroxycaproic acid and ester thereof by using tetrahydrofurfuryl acetic acid and ester thereof | 中国科学院兰州化学物理研究所 | 2021-05-28 | — | — | CN | claimed |
| CN-106938980-A | The preparation method of the carboxylic acid of one kind N of 5 benzyl 5 miscellaneous spiral shell [2.4] heptane 1 | 无锡捷化医药科技有限公司 | 2017-07-11 | — | — | CN | claimed |
| CN-105646634-A | Preparation method of impurities of obeticholic acid | 中国药科大学 | 2016-06-08 | — | — | CN | claimed |
| US-8680334-B2 | Process for the preparation of iosimenol | MALLINCKRODT LLC (US) | 2014-03-25 | — | — | US | claimed |
| US-20130261338-A1 | Process for the Preparation of Iosimenol | MALLINCKRODT LLC (US) | 2013-10-03 | — | — | US | claimed |
| CN-103265678-A | Preparation method of xylitol aroma type polyurethane | STATE GRID CORP CHINA | 2013-08-28 | — | — | CN | claimed |
| EP-2240432-B1 | PROCESS FOR THE PREPARATION OF IOSIMENOL | MALLINCKRODT LLC (US) | 2012-07-04 | — | — | EP | claimed |
| US-20100280270-A1 | Process for the Prepartion of Iosimenol | MNK 2011 LLC (F/K/A MALLINCKRODT INC.) | 2010-11-04 | — | — | US | claimed |
| EP-2240432-A1 | PROCESS FOR THE PREPARATION OF IOSIMENOL | Mallinckrodt Inc. (US) | 2010-10-20 | — | — | EP | claimed |
| CN-101817742-A | Crystal form X of sofalcone, preparation method and use thereof | TIANJIN INST PHARM RESEARCH | 2010-09-01 | — | — | CN | claimed |
| WO-2009091758-A1 | PROCESS FOR THE PREPARATION OF IOSIMENOL | MALLINCKRODT INC. (US) | 2009-07-23 | — | — | WO | claimed |
| EP-0284966-B1 | Processes for the preparation of benzo (chalcogeno)[4,3,2-CD] indazoles | WARNER-LAMBERT COMPANY (US) | 1992-01-02 | — | — | EP | claimed |
| EP-0144386-B1 | NOVEL PREPARATION OF NUCLEOSIDE PHOSPHORAMIDITE INTERMEDIATES | BECKMAN INSTRUMENTS, INC. (US) | 1989-09-06 | — | — | EP | claimed |
| US-4806654-A | Processes for the preparation of benzo(chalcogeno)(4,3,2-cd)indazoles and intermediates thereof | WARNER-LAMBERT COMPANY (US) | 1989-02-21 | — | — | US | claimed |
| EP-0284966-A1 | Processes for the preparation of benzo (chalcogeno)[4,3,2-CD] indazoles | WARNER-LAMBERT COMPANY (US) | 1988-10-05 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280270-A1 | Process for the Prepartion of Iosimenol | DHCR24, DRD4, NONO | ALDH1A1 1647/4885LMNA 713/4885HSD17B10 3130/4885 |
| US-20130261338-A1 | Process for the Preparation of Iosimenol | ITPR3, ITPR2, DHCR24 | ALDH1A1 2309/4885LMNA 1642/4885HSD17B10 3090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.