SCHEMBL6544950

SCHEMBL6544950

O=P(Cc1ccc2ccccc2c1-c1c(CP(=O)(c2cc(F)cc(F)c2)c2cc(F)cc(F)c2)ccc2ccccc12)(c1cc(F)cc(F)c1)c1cc(F)cc(F)c1

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ACP3 P15309 1/20 0.37
CES1 P23141 1/20 0.35
CYP2A6 P11509 2/20 0.34
CYP1A2 P05177 1/20 0.34
HPRT1 P00492 1/20 0.33
HTT P42858 3/20 0.33
ALDH1A1 P00352 3/20 0.33
HPGD P15428 1/20 0.33
WDR5 P61964 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
DNMT1 P26358 1/20 0.32
HSD17B10 Q99714 2/20 0.32
HIF1A Q16665 1/20 0.32
CYP1B1 Q16678 1/20 0.32
MAPK14 Q16539 1/20 0.32
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7777329 0.89 ACP3 (0.39) ACP3CES1CYP2A6CYP1A2HTT
SCHEMBL5692996 0.87 ACP3 (0.36) ACP3CES1CYP1A2HPRT1HTT
SCHEMBL7777320 0.87 CES1 (0.42) ACP3CES1CYP1A2HTTALDH1A1
SCHEMBL7775603 0.83 HTT (0.46) ACP3HTTALDH1A1HPGDWDR5
SCHEMBL5692296 0.82 HTT (0.41) ACP3CYP2A6CYP1A2HTTALDH1A1
SCHEMBL8679313 0.81 ACP3 (0.35) ACP3CES1CYP1A2HTTALDH1A1
SCHEMBL5691678 0.79 ACP3 (0.39) ACP3CES1CYP2A6HPRT1ALDH1A1
SCHEMBL5691647 0.78 ACP3 (0.36) ACP3CES1CYP1A2HPRT1ALDH1A1
SCHEMBL8678993 0.78 CES1 (0.38) ACP3CES1HTTALDH1A1HPGD
SCHEMBL7771223 0.77 ACP3 (0.40) ACP3CYP1A2HTTHPGDCYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1373279-A1 METHOD FOR PRODUCING DIPHOSPHINES AND THE USE THEREOF Oxeno Olefinchemie GmbH (DE) 2004-01-02 EP disclosed
WO-2002076996-A1 METHOD FOR PRODUCING DIPHOSPHINES AND THE USE THEREOF OXENO OLEFINCHEMIE GMBH (DE) 2002-10-03 WO disclosed