Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | ACP3 | P15309 | 1/20 | 0.37 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | TYMP | P19971 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7777320 | 0.90 | CES1 (0.42) | CES1ACP3HTTL3MBTL1KMT2A | |
| SCHEMBL8679316 | 0.89 | CYP3A4 (0.42) | ACP3DNMT1HTTL3MBTL1KMT2A | |
| SCHEMBL8679313 | 0.87 | ACP3 (0.35) | CES1ACP3DNMT1HTTKMT2A | |
| SCHEMBL8676854 | 0.79 | ACP3 (0.36) | ACP3HTTKMT2AMEN1MAPT | |
| SCHEMBL7777329 | 0.78 | ACP3 (0.39) | CES1ACP3HTTL3MBTL1KMT2A | |
| SCHEMBL7775603 | 0.78 | HTT (0.46) | ACP3HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL6544950 | 0.78 | ACP3 (0.37) | CES1ACP3DNMT1HTTL3MBTL1 | |
| SCHEMBL8676233 | 0.76 | ALDH1A1 (0.38) | ACP3DNMT1HTTKMT2AMEN1 | |
| SCHEMBL5692996 | 0.74 | ACP3 (0.36) | CES1ACP3DNMT1HTTL3MBTL1 | |
| SCHEMBL5691678 | 0.72 | ACP3 (0.39) | CES1ACP3DNMT1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767317-A | Process for preparing 2,2'-bis(diphenylphosphinylmethyl)-1,1'-binaphthyls and new compounds from this class of substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-06-16 | — | — | US | disclosed |