Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3910063 | 0.82 | LMNA (0.48) | LMNAHPGDGLARECQLLTB4R | |
| SCHEMBL3913645 | 0.82 | LMNA (0.48) | LMNAHPGDGLARECQLLTB4R | |
| SCHEMBL3910061 | 0.82 | LMNA (0.48) | LMNAHPGDGLARECQLLTB4R | |
| SCHEMBL8797904 | 0.76 | DPP4 (0.36) | LMNAHPGDGLARECQLMEN1 | |
| SCHEMBL8797903 | 0.76 | DPP4 (0.36) | LMNAHPGDGLARECQLMEN1 | |
| Hydroxyamine SCHEMBL23849548 | 0.76 | LMNA (0.46) | LMNAHPGDGLARECQLLTB4R | |
| SCHEMBL77705 | 0.75 | LMNA (0.50) | LMNAHPGDGLARECQLLTB4R | |
| SCHEMBL8206022 | 0.75 | LMNA (0.50) | LMNAHPGDGLARECQLLTB4R | |
| Hydrochloric Acid SCHEMBL1036864 | 0.73 | LMNA (0.48) | LMNAHPGDGLARECQLLTB4R | |
| SCHEMBL8211316 | 0.73 | LMNA (0.48) | LMNAHPGDGLARECQLLTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6812368-B2 | CATALYTIC HYDROGENATION USING MAGNESIUM COMPOUND AND PLATINUM | SOLVIAS AG (CH) | 2004-11-02 | — | — | US | disclosed |
| US-20040010154-A1 | Diastereoselective hydrogenation of 1,3-hydroxyketones | SOLVIAS AG (CH) | 2004-01-15 | — | — | US | disclosed |
| EP-1378501-A1 | Diastereoselective hydrogenation of beta-hydroxyketones | Solvias AG (CH) | 2004-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040010154-A1 | Diastereoselective hydrogenation of 1,3-hydroxyketones | HK1, HSD17B7, GRIK1 | LMNA 4430/4885HPGD 341/4885GLA 4053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.