Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1048614 | 1.00 | TSHR (0.62) | TSHRLMNAALDH1A1SIGMAR1LOXL2 | |
| Hydrochloric Acid SCHEMBL1169677 | 0.98 | TSHR (0.61) | TSHRLMNAALDH1A1SIGMAR1LOXL2 | |
| Oxalic Acid SCHEMBL7219123 | 0.92 | TSHR (0.54) | TSHRLMNAALDH1A1SIGMAR1CYP2D6 | |
| Oxalic Acid SCHEMBL7219128 | 0.92 | TSHR (0.54) | TSHRLMNAALDH1A1SIGMAR1CYP2D6 | |
| SCHEMBL6998770 | 0.89 | TSHR (0.59) | TSHRLMNAALDH1A1SIGMAR1LOXL2 | |
| SCHEMBL1816182 | 0.85 | TSHR (0.62) | TSHRLMNAALDH1A1SIGMAR1CYP1A2 | |
| SCHEMBL43922 | 0.85 | TSHR (0.67) | TSHRLMNAALDH1A1LOXL2CYP1A2 | |
| SCHEMBL30504205 | 0.85 | TSHR (0.67) | TSHRLMNAALDH1A1LOXL2CYP1A2 | |
| Hydrochloric Acid SCHEMBL1017929 | 0.83 | TSHR (0.65) | TSHRLMNAALDH1A1LOXL2CYP1A2 | |
| SCHEMBL7399400 | 0.83 | TSHR (0.65) | TSHRLMNAALDH1A1SIGMAR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1372632-A1 | PROLIFERATIVE ACTIVATOR RECEPTOR (PPAR) COMPOUNDS | Pfizer Products Inc. (US) | 2004-01-02 | — | — | EP | disclosed |
| US-20020169192-A1 | PPAR compounds | HAYWARD CHERYL M (US) | 2002-11-14 | — | — | US | disclosed |
| WO-2002064130-A1 | PROLIFERATIVE ACTIVATOR RECEPTOR (PPAR) COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2002-08-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020169192-A1 | PPAR compounds | PPARA, PPARG, PPARD | TSHR 369/4885LMNA 958/4885ALDH1A1 1922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.