Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | GRM8 | O00222 | 1/20 | 0.48 |
| ▸ | GRM6 | O15303 | 1/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL7219123 | 1.00 | TSHR (0.54) | TSHRALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL6545015 | 0.92 | TSHR (0.62) | TSHRALDH1A1LMNACYP2D6CYP2C9 | |
| SCHEMBL1048614 | 0.92 | TSHR (0.62) | TSHRALDH1A1LMNACYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL1169677 | 0.90 | TSHR (0.61) | TSHRALDH1A1LMNACYP2D6CYP2C9 | |
| SCHEMBL5738137 | 0.83 | ALDH1A1 (0.58) | TSHRALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL6998770 | 0.82 | TSHR (0.59) | TSHRALDH1A1LMNACYP2D6CYP2C9 | |
| SCHEMBL81066 | 0.81 | FFAR1 (0.66) | TSHRALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL8871859 | 0.81 | FFAR1 (0.66) | TSHRALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL15921150 | 0.80 | TSHR (0.65) | TSHRALDH1A1SMN1; SMN2LMNAPOLB | |
| SCHEMBL31033035 | 0.79 | TRPV1 (0.56) | TSHRALDH1A1SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596734-B1 | Method for stimulating, regulating and modulating metabolism of fats in adipose tissue in mammals, comprising administering to a mammal an effective amount of a beta 3- adrenoreceptor agonist | MOLECULAR DESIGN INTERNATIONAL, INC. | 2003-07-22 | — | — | US | disclosed |