SCHEMBL654510

SCHEMBL654510

COC(OC)c1ccc(Cl)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.48
AOC3 Q16853 2/20 0.47
SLC6A4 P31645 1/20 0.47
IDO1 P14902 3/20 0.44
TDO2 P48775 3/20 0.44
TSHR P16473 2/20 0.44
MAPK1 P28482 2/20 0.44
HIF1A Q16665 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
LMNA P02545 3/20 0.42
TP53 P04637 1/20 0.42
HPGD P15428 1/20 0.42
CYP2A6 P11509 1/20 0.42
ALOX15 P16050 1/20 0.41
BRD4 O60885 1/20 0.40
CYP19A1 P11511 3/20 0.39
MAPT P10636 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8955219 0.86 CA12 (0.35) AOC3SLC6A4TSHRMAPK1TDP1
SCHEMBL250661 0.81 IDO1 (0.43) IDO1MAPK1HIF1ALMNAHPGD
SCHEMBL10254167 0.81 AOC3 (0.42) ADRB2AOC3SLC6A4IDO1TDO2
SCHEMBL791590 0.79 IDO1 (0.56) ADRB2AOC3SLC6A4IDO1TDO2
SCHEMBL29098748 0.78 ALOX15 (0.63) ADRB2AOC3SLC6A4IDO1TDO2
SCHEMBL29098746 0.78 ALOX15 (0.46) ADRB2AOC3SLC6A4LMNAALOX15
SCHEMBL15350067 0.78 TSHR (0.34) TSHRMAPK1TDP1
SCHEMBL21162070 0.78 TSHR (0.34) TSHRMAPK1TDP1
SCHEMBL15854056 0.77 ADRB2 (0.52) ADRB2AOC3SLC6A4IDO1TDO2
SCHEMBL11403506 0.77 AOC3 (0.50) ADRB2AOC3SLC6A4IDO1TDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116425615-B Industrial continuous production method of 4-chlorobenzaldehyde dimethyl acetal 江苏剑牌农化股份有限公司 2025-02-07 CN claimed
CN-116425615-A Industrial continuous production method of 4-chlorobenzaldehyde dimethyl acetal 江苏剑牌农化股份有限公司 2023-07-14 CN claimed
CN-116425615-B Industrial continuous production method of 4-chlorobenzaldehyde dimethyl acetal 江苏剑牌农化股份有限公司 2025-02-07 CN disclosed
CN-116425615-B Industrial continuous production method of 4-chlorobenzaldehyde dimethyl acetal 江苏剑牌农化股份有限公司 2025-02-07 CN disclosed
CN-116425615-B Industrial continuous production method of 4-chlorobenzaldehyde dimethyl acetal 江苏剑牌农化股份有限公司 2025-02-07 CN disclosed
US-20240132440-A1 METHOD FOR THE PRODUCTION OF D-ERYTHRO-SPHINGOSINE AND ANALOGS THEREOF CARBOCODE S A (PT) 2024-04-25 US disclosed
EP-4281435-A1 METHOD FOR THE PRODUCTION OF D-ERYTHRO-SPHINGOSINE AND ANALOGS THEREOF CARBOCODE S.A. (PT) 2023-11-29 EP disclosed
CN-116964029-A Method for producing D-erythro-sphingosine and analogues thereof 碳码股份公司 2023-10-27 CN disclosed
CN-116554221-A Synthesis method of alpha-alkoxy p-chlorobenzyl phosphate 辽宁众辉生物科技有限公司 2023-08-08 CN disclosed
CN-116425615-A Industrial continuous production method of 4-chlorobenzaldehyde dimethyl acetal 江苏剑牌农化股份有限公司 2023-07-14 CN disclosed
CN-116425615-A Industrial continuous production method of 4-chlorobenzaldehyde dimethyl acetal 江苏剑牌农化股份有限公司 2023-07-14 CN disclosed
US-5066681-A Fungicides BAYER AKTIENGESELLSCHAFT (DE) 1991-11-19 US disclosed
EP-0363726-A2 1-Trifluoromethyl-1-nitro-2-alkoxy-2-aryl ethanes, their preparation and antimycotic preparations containing them BAYER AG (DE) 1990-04-18 EP disclosed
US-4699698-A Preparation of benzoic acid ortho-esters and novel compounds of this type BASF AKTIENGESELLSCHAFT (DE) 1987-10-13 US disclosed
EP-0179289-B1 METHOD FOR PRODUCING AROMATIC CARBOXYLIC ESTERS BASF Aktiengesellschaft (DE) 1987-07-08 EP disclosed
EP-0212509-A1 Process for manufacturing benzoic-acid orthoesters, and compounds of this class BASF Aktiengesellschaft (DE) 1987-03-04 EP disclosed
US-4612092-A TRIARYLAMINE, ELECTROLYSIS BASF AKTIENGESELLSCHAFT (DE) 1986-09-16 US disclosed
EP-0179289-A1 Method for producing aromatic carboxylic esters BASF Aktiengesellschaft (DE) 1986-04-30 EP disclosed
US-4246021-A Imidazole derivatives MAY & BAKER LIMITED (GB) 1981-01-20 US disclosed
US-4167565-A Adenosine-5'-carboxamides and method of use ABBOTT LABORATORIES (US) 1979-09-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240132440-A1 METHOD FOR THE PRODUCTION OF D-ERYTHRO-SPHINGOSINE AND ANALOGS THEREOF CERT1, S1PR3, S1PR4 ADRB2 2256/4885AOC3 113/4885SLC6A4 2687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.