Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 14/20 | 0.52 |
| ▸ | PPARG | P37231 | 12/20 | 0.52 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | BMP1 | P13497 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6364742 | 1.00 | PPARA (0.52) | PPARAPPARGPPARDCNR2TAS2R14 | |
| SCHEMBL6363875 | 0.94 | PPARA (0.54) | PPARAPPARGPPARDCNR2CYP2D6 | |
| SCHEMBL6359208 | 0.90 | PPARA (0.44) | PPARAPPARGPPARDCNR2TAS2R14 | |
| SCHEMBL6361181 | 0.90 | PPARA (0.53) | PPARAPPARGPPARDCNR2TAS2R14 | |
| SCHEMBL6357807 | 0.88 | PPARA (0.53) | PPARAPPARGPPARDCNR2TAS2R14 | |
| SCHEMBL6358183 | 0.83 | PPARA (0.59) | PPARAPPARGPPARDCNR2 | |
| SCHEMBL6357740 | 0.82 | PPARA (0.54) | PPARAPPARGTAS2R14BMP1 | |
| SCHEMBL6545681 | 0.82 | PPARA (0.54) | PPARAPPARGTAS2R14BMP1 | |
| SCHEMBL6359838 | 0.80 | PPARA (0.68) | PPARAPPARGPPARD | |
| SCHEMBL6363553 | 0.79 | BMP1 (0.57) | PPARAPPARGCNR2TAS2R14BMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1372632-A1 | PROLIFERATIVE ACTIVATOR RECEPTOR (PPAR) COMPOUNDS | Pfizer Products Inc. (US) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002064130-A1 | PROLIFERATIVE ACTIVATOR RECEPTOR (PPAR) COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2002-08-22 | — | — | WO | disclosed |