Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.54 |
| ▸ | PPARG | P37231 | 7/20 | 0.54 |
| ▸ | BMP1 | P13497 | 3/20 | 0.46 |
| ▸ | TAS2R14 | Q9NYV8 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | P4HB | P07237 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6545681 | 1.00 | PPARA (0.54) | PPARAPPARGBMP1TAS2R14CA12 | |
| SCHEMBL6363553 | 0.93 | BMP1 (0.57) | PPARAPPARGBMP1TAS2R14 | |
| SCHEMBL6357807 | 0.93 | PPARA (0.53) | PPARAPPARGBMP1TAS2R14CA12 | |
| SCHEMBL6363875 | 0.88 | PPARA (0.54) | PPARAPPARGCETP | |
| SCHEMBL6545146 | 0.82 | PPARA (0.52) | PPARAPPARGBMP1TAS2R14 | |
| SCHEMBL6364742 | 0.82 | PPARA (0.52) | PPARAPPARGBMP1TAS2R14 | |
| SCHEMBL13508458 | 0.81 | PPARG (0.64) | PPARAPPARGBMP1TAS2R14CA12 | |
| SCHEMBL6359007 | 0.81 | PPARA (0.61) | PPARAPPARGCA12CA1CA2 | |
| SCHEMBL6363253 | 0.80 | PPARA (0.57) | PPARAPPARGCA12CA1CA2 | |
| SCHEMBL6364698 | 0.80 | PPARA (0.58) | PPARAPPARGCETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050075377-A1 | PPAR compounds | PFIZER INC | 2005-04-07 | — | — | US | disclosed |
| US-20020169192-A1 | PPAR compounds | HAYWARD CHERYL M (US) | 2002-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020169192-A1 | PPAR compounds | PPARA, PPARG, PPARD | PPARA 1/4885PPARG 2/4885BMP1 2433/4885 |
| US-20050075377-A1 | PPAR compounds | PPARA, PPARG, PPARD | PPARA 1/4885PPARG 2/4885BMP1 2433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.