Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 10/20 | 0.42 |
| ▸ | PPARG | P37231 | 9/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PTGIR | P43119 | 1/20 | 0.33 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6545685 | 0.85 | PPARA (0.45) | PPARAPPARGSIGMAR1PTGIR | |
| SCHEMBL6545236 | 0.77 | PPARA (0.48) | PPARAPPARG | |
| SCHEMBL6364742 | 0.75 | PPARA (0.52) | PPARAPPARG | |
| SCHEMBL6545146 | 0.75 | PPARA (0.52) | PPARAPPARG | |
| SCHEMBL6357807 | 0.71 | PPARA (0.53) | PPARAPPARG | |
| SCHEMBL6358183 | 0.69 | PPARA (0.59) | PPARAPPARG | |
| SCHEMBL6363875 | 0.68 | PPARA (0.54) | PPARAPPARG | |
| SCHEMBL6361181 | 0.68 | PPARA (0.53) | PPARAPPARG | |
| SCHEMBL6359208 | 0.67 | PPARA (0.44) | PPARAPPARG | |
| SCHEMBL6359838 | 0.66 | PPARA (0.68) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1372632-A1 | PROLIFERATIVE ACTIVATOR RECEPTOR (PPAR) COMPOUNDS | Pfizer Products Inc. (US) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002064130-A1 | PROLIFERATIVE ACTIVATOR RECEPTOR (PPAR) COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2002-08-22 | — | — | WO | disclosed |