Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.48 |
| ▸ | PPARG | P37231 | 4/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6545148 | 0.77 | PPARA (0.42) | PPARAPPARG | |
| SCHEMBL6363875 | 0.75 | PPARA (0.54) | PPARAPPARGCYP2D6 | |
| SCHEMBL6545685 | 0.74 | PPARA (0.45) | PPARAPPARG | |
| SCHEMBL6364312 | 0.74 | PPARG (0.58) | PPARAPPARG | |
| SCHEMBL6544734 | 0.72 | ADRB1 (0.46) | PPARAPPARGCYP2D6KCNH2ADRB3 | |
| SCHEMBL6545718 | 0.72 | PPARG (0.46) | PPARAPPARGCYP2D6 | |
| SCHEMBL6358041 | 0.72 | PPARA (0.53) | PPARAPPARGCYP2D6KCNH2 | |
| SCHEMBL6357740 | 0.71 | PPARA (0.54) | PPARAPPARG | |
| SCHEMBL6545681 | 0.71 | PPARA (0.54) | PPARAPPARG | |
| SCHEMBL6545146 | 0.70 | PPARA (0.52) | PPARAPPARGCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1372632-A1 | PROLIFERATIVE ACTIVATOR RECEPTOR (PPAR) COMPOUNDS | Pfizer Products Inc. (US) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002064130-A1 | PROLIFERATIVE ACTIVATOR RECEPTOR (PPAR) COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2002-08-22 | — | — | WO | disclosed |