Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | DGKA | P23743 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PAM | P19021 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6545301 | 0.90 | TSHR (0.46) | TSHRLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL4645722 | 0.89 | TSHR (0.39) | TSHRDGKACYP1A2LMNAALDH1A1 | |
| SCHEMBL4642597 | 0.87 | KDM4E (0.39) | TSHRDGKALMNAALDH1A1PAM | |
| SCHEMBL4647504 | 0.87 | TSHR (0.38) | TSHRDGKACYP1A2LMNAALDH1A1 | |
| SCHEMBL4641699 | 0.87 | TSHR (0.38) | TSHRDGKACYP1A2ALDH1A1 | |
| SCHEMBL4645088 | 0.86 | TSHR (0.37) | TSHRDGKACYP1A2LMNAALDH1A1 | |
| SCHEMBL4641761 | 0.84 | TSHR (0.35) | TSHRALDH1A1 | |
| SCHEMBL4643606 | 0.82 | TSHR (0.33) | TSHRALDH1A1 | |
| SCHEMBL4644855 | 0.82 | TSHR (0.33) | TSHRALDH1A1 | |
| SCHEMBL6546145 | 0.80 | TSHR (0.44) | TSHRDGKALMNAALDH1A1PAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004005302-A1 | PROCESS FOR THE PREPARATION OF ACYLOXYSILANES | SIGMA COATINGS B.V. (NL) | 2004-01-15 | — | — | WO | disclosed |
| EP-1378514-A1 | Process for the preparation of acyloxysilanes | SigmaKalon Group B.V. (NL) | 2004-01-07 | — | — | EP | disclosed |