Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | PAM | P19021 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14735468 | 0.96 | CES1 (0.41) | TSHRDGKALMNAPAMMAPT | |
| SCHEMBL6545806 | 0.94 | TSHR (0.39) | TSHRDGKALMNAPAMCES2 | |
| SCHEMBL6661355 | 0.93 | TSHR (0.52) | TSHRPAMMAPTALDH1A1TDP1 | |
| SCHEMBL28423837 | 0.92 | DGKA (0.52) | TSHRDGKALMNAPAMMAPT | |
| SCHEMBL2599070 | 0.92 | ALDH1A1 (0.44) | TSHRDGKALMNAPAMCES2 | |
| SCHEMBL4644370 | 0.90 | DGKA (0.37) | TSHRDGKALMNAPAMMAPT | |
| SCHEMBL4645339 | 0.89 | DGKA (0.36) | TSHRDGKALMNAPAMMAPT | |
| SCHEMBL4643673 | 0.89 | DGKA (0.40) | TSHRDGKALMNAPAMMAPT | |
| SCHEMBL4644917 | 0.89 | FAAH (0.39) | TSHRDGKALMNAPAMMAPT | |
| SCHEMBL4643559 | 0.88 | NAAA (0.39) | TSHRDGKALMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004005302-A1 | PROCESS FOR THE PREPARATION OF ACYLOXYSILANES | SIGMA COATINGS B.V. (NL) | 2004-01-15 | — | — | WO | disclosed |
| EP-1378514-A1 | Process for the preparation of acyloxysilanes | SigmaKalon Group B.V. (NL) | 2004-01-07 | — | — | EP | disclosed |