SCHEMBL4642597

SCHEMBL4642597

CC[Si](C)(C)OC(=O)CCCCO

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
TSHR P16473 2/20 0.38
GPR84 Q9NQS5 1/20 0.37
FFAR1 O14842 1/20 0.37
FFAR4 Q5NUL3 1/20 0.37
DGKA P23743 1/20 0.35
MAPT P10636 1/20 0.35
MAPK1 P28482 1/20 0.35
LMNA P02545 4/20 0.33
VCAM1 P19320 1/20 0.33
DUSP3 P51452 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
PAM P19021 2/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4645722 0.94 TSHR (0.39) KDM4ESMN1; SMN2TSHRDGKAMAPT
SCHEMBL6545156 0.87 TSHR (0.50) TSHRDGKAMAPTMAPK1LMNA
SCHEMBL4641761 0.85 TSHR (0.35) TSHRALDH1A1
SCHEMBL4643673 0.83 DGKA (0.40) KDM4ESMN1; SMN2TSHRDGKAMAPT
SCHEMBL6545301 0.83 TSHR (0.46) KDM4ETSHRMAPTLMNAMEN1
SCHEMBL4645088 0.82 TSHR (0.37) TSHRDGKAMAPTMAPK1LMNA
SCHEMBL4642065 0.82 KDM4E (0.41) KDM4ESMN1; SMN2TSHRGPR84FFAR1
SCHEMBL4643892 0.81 GPR84 (0.41) KDM4ESMN1; SMN2TSHRGPR84FFAR1
SCHEMBL4641699 0.80 TSHR (0.38) KDM4ESMN1; SMN2TSHRDGKAALDH1A1
SCHEMBL4647504 0.80 TSHR (0.38) TSHRDGKALMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed