SCHEMBL6545333

SCHEMBL6545333

CC(CN[C@@H](CC(=O)O)C(=O)O)CN[C@@H](CC(=O)O)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.40
CA4 P22748 1/20 0.40
MME P08473 2/20 0.40
TDP1 Q9NUW8 1/20 0.37
FOLH1 Q04609 2/20 0.36
NAALAD2 Q9Y3Q0 2/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
GNPAT O15228 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7611735 1.00 CA2 (0.40) CA2CA4MMETDP1FOLH1
SCHEMBL14200542 0.87 MAPT (0.44) CA2CA4MMETDP1FOLH1
SCHEMBL2911554 0.85 CA2 (0.39) CA2CA4MMETDP1FOLH1
SCHEMBL12541972 0.85 APAF1 (0.46) CA2CA4MMEFOLH1NAALAD2
SCHEMBL2915369 0.85 CA2 (0.43) CA2CA4MMETDP1FOLH1
SCHEMBL2915366 0.85 CA2 (0.43) CA2CA4MMETDP1FOLH1
SCHEMBL2911556 0.85 CA2 (0.39) CA2CA4MMETDP1FOLH1
SCHEMBL14721337 0.84 GNPAT (0.36) CA2CA4MMEGNPAT
SCHEMBL14721339 0.84 GNPAT (0.36) CA2CA4MMEGNPAT
SCHEMBL27383424 0.83 CA2 (0.42) CA2CA4MMETDP1FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0805211-B1 Process for producing optically active aminopolycarboxylic acid MITSUBISHI RAYON CO (JP) 2002-10-02 EP claimed
US-5981238-A REACTING A DIAMINE AND FUMARIC ACID USING MICROORGANISM OR EXTRACT HAVING LYASE ACTIVITY; PRESENCE OF ALKALINE EARTH METAL, IRON, ZINC, COPPER, NICKEL, ALUMINUM, TITANIUM OR MANGANESE IONS INCREASES YIELD BY FORMING STABLE COMPLEXES MITSUBISHI RAYON CO., LTD. (JP) 1999-11-09 US claimed
EP-0805211-A2 Process for producing optically active aminopolycarboxylic acid NITTO CHEMICAL INDUSTRY CO., LTD. (JP) 1997-11-05 EP claimed
EP-0927762-B1 Method for removing fumarase activity, Microorganisms obtainable by the method and production of optically active aminopolycarboxylic acids using the microorganisms MITSUBISHI RAYON CO (JP) 2004-01-07 EP disclosed
US-6103508-A REMOVING ENZYME ACTIVITY FROM A BREVIBACTERIUM OR PROTEIN OF BREVIBACTERIUM; INCUBATION OF BREVIBACTERIUM OR PRODUCT IN ALKALINE SOLUTION AND SALT OF AN ACID MITSUBISHI RAYON CO., LTD. (JP) 2000-08-15 US disclosed
EP-0927762-A2 Method for removing fumarase activity, Microorganisms obtainable by the method and production of optically active aminopolycarboxylic acids using the microorganisms Mitsubishi Rayon Co., Ltd. (JP) 1999-07-07 EP disclosed