SCHEMBL6545549

SCHEMBL6545549

CCCCC=C(C(=O)O)C(F)(F)F

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 1/20 0.52
FAAH O00519 11/20 0.44
CES1 P23141 7/20 0.44
CES2 O00748 5/20 0.44
MEN1 O00255 1/20 0.44
CYP1A2 P05177 1/20 0.44
KMT2A Q03164 1/20 0.44
HSD17B10 Q99714 1/20 0.44
GRIK1 P39086 1/20 0.42
F7 P08709 1/20 0.41
F3 P13726 1/20 0.41
EPHX1 P07099 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20598101 0.94 EP300 (0.60) EP300FAAHCES1CES2MEN1
SCHEMBL7556656 0.82 EP300 (0.53) EP300FAAHCYP1A2KMT2AHSD17B10
SCHEMBL7556653 0.82 EP300 (0.53) EP300FAAHCYP1A2KMT2AHSD17B10
SCHEMBL28504022 0.80 EP300 (0.52) EP300FAAHCYP1A2KMT2AHSD17B10
SCHEMBL2852706 0.79 GRIK1 (0.35) EP300FAAHCES1CES2MEN1
SCHEMBL2852703 0.79 GRIK1 (0.35) EP300FAAHCES1CES2MEN1
SCHEMBL28569623 0.78 FAAH (0.45) EP300FAAHCES1CES2MEN1
SCHEMBL7124103 0.76 EP300 (0.62) EP300FAAHCYP1A2KMT2AHSD17B10
SCHEMBL5271639 0.76 EP300 (0.62) EP300FAAHCYP1A2KMT2AHSD17B10
SCHEMBL7758689 0.76 EP300 (0.47) EP300FAAHCYP1A2KMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116396478-A Preparation method of styrene thermoplastic polymer material 北京化工大学 2023-07-07 CN disclosed
EP-1379331-A2 PROCESS FOR PRODUCING FILM FORMING RESINS FOR PHOTORESIST COMPOSITIONS CLARIANT INTERNATIONAL LTD. (CH) 2004-01-14 EP disclosed
WO-2002084402-A2 PROCESS FOR PRODUCING FILM FORMING RESINS FOR PHOTORESIST COMPOSITIONS CLARIANT INTERNATIONAL LTD (CH) 2002-10-24 WO disclosed
CN-1314906-A Salts of paroxetine SMITHKLINE BEECHAM PLC (GB) 2001-09-26 CN disclosed