SCHEMBL6545664

SCHEMBL6545664

CC(C)c1ccccc1CC(C)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.47
MAOA P21397 3/20 0.45
MAOB P27338 3/20 0.45
NISCH Q9Y2I1 3/20 0.45
AOC3 Q16853 2/20 0.42
TRPA1 O75762 4/20 0.41
RIPK1 Q13546 1/20 0.41
ALDH1A1 P00352 1/20 0.39
GABRA1 P14867 1/20 0.39
GABRB2 P47870 1/20 0.39
P2RX7 Q99572 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19478609 0.84 GABRA1 (0.52) TAAR1MAOAMAOBNISCHAOC3
SCHEMBL20235201 0.84 TAAR1 (0.40) TAAR1MAOAMAOBNISCHAOC3
SCHEMBL20273169 0.84 TAAR1 (0.40) TAAR1MAOAMAOBNISCHAOC3
SCHEMBL21104854 0.79 MAOA (0.45) TAAR1MAOAMAOBNISCHAOC3
SCHEMBL6681972 0.79 GABRA1 (0.52) GABRA1GABRB2
SCHEMBL6547026 0.78 SLC6A2 (0.49) TAAR1MAOAMAOBNISCHAOC3
SCHEMBL6547230 0.78 SLC6A2 (0.49) TAAR1MAOAMAOBNISCHAOC3
Isopropylbenzene SCHEMBL7651424 0.76 HTT (0.44) TAAR1GABRA1GABRB2
SCHEMBL25215353 0.76 SLC6A2 (0.47) TAAR1AOC3TRPA1
SCHEMBL1952363 0.76 SLC6A2 (0.47) TAAR1AOC3TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed