Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.49 |
| ▸ | PPARG | P37231 | 9/20 | 0.49 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | ARG1 | P05089 | 1/20 | 0.36 |
| ▸ | ARG2 | P78540 | 1/20 | 0.36 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6545721 | 0.87 | PPARA (0.46) | PPARAPPARGGGPS1S1PR4S1PR1 | |
| SCHEMBL6544739 | 0.79 | PPARA (0.48) | PPARAPPARGS1PR4S1PR1S1PR3 | |
| SCHEMBL6545718 | 0.76 | PPARG (0.46) | PPARAPPARG | |
| SCHEMBL6545717 | 0.76 | PPARG (0.46) | PPARAPPARG | |
| SCHEMBL6363253 | 0.74 | PPARA (0.57) | PPARAPPARGCETP | |
| SCHEMBL6364312 | 0.71 | PPARG (0.58) | PPARAPPARG | |
| SCHEMBL6363875 | 0.69 | PPARA (0.54) | PPARAPPARGCETP | |
| SCHEMBL6357740 | 0.69 | PPARA (0.54) | PPARAPPARGCETP | |
| SCHEMBL6545681 | 0.69 | PPARA (0.54) | PPARAPPARGCETP | |
| SCHEMBL29129794 | 0.68 | PPARG (0.51) | PPARAPPARGPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1372632-A1 | PROLIFERATIVE ACTIVATOR RECEPTOR (PPAR) COMPOUNDS | Pfizer Products Inc. (US) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002064130-A1 | PROLIFERATIVE ACTIVATOR RECEPTOR (PPAR) COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2002-08-22 | — | — | WO | disclosed |