Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4795228 | 0.76 | SLC6A12 (0.32) | — | |
| SCHEMBL7438175 | 0.74 | SLC1A2 (0.37) | MEN1BLMKMT2ASLC1A2 | |
| SCHEMBL10964534 | 0.71 | — | — | |
| SCHEMBL27352103 | 0.70 | AKR1C3 (0.37) | SLC1A2SLC1A1 | |
| SCHEMBL4520201 | 0.69 | — | — | |
| SCHEMBL27680982 | 0.66 | — | — | |
| SCHEMBL10974330 | 0.64 | — | — | |
| SCHEMBL6921475 | 0.62 | CYP2D6 (0.34) | MEN1BLMKMT2A | |
| SCHEMBL6831849 | 0.62 | GAA (0.31) | MEN1BLMKMT2A | |
| SCHEMBL4615472 | 0.62 | CYP2D6 (0.34) | MEN1BLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1380590-A1 | Method for synthesis of perindopril and its pharmaceutically acceptable salts | Les Laboratoires Servier (FR) | 2004-01-14 | — | — | EP | disclosed |
| EP-1367062-A1 | Method for synthesis of perindopril and its pharmaceutically acceptable salts | Les Laboratoires Servier (FR) | 2003-12-03 | — | — | EP | disclosed |
| EP-1321471-A1 | Method for synthesis of perindopril and its pharmaceutically acceptable salts | LES LABORATOIRES SERVIER (FR) | 2003-06-25 | — | — | EP | disclosed |