Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6545783 | 0.74 | MEN1 (0.34) | SLC1A2MEN1BLMKMT2A | |
| SCHEMBL2308470 | 0.68 | SLC1A2 (0.34) | SLC1A2 | |
| SCHEMBL20788739 | 0.67 | TSHR (0.31) | BLM | |
| SCHEMBL9630842 | 0.64 | POLB (0.43) | KMT2A | |
| SCHEMBL30915787 | 0.63 | — | — | |
| SCHEMBL25320147 | 0.62 | EGLN1 (0.31) | — | |
| SCHEMBL27545542 | 0.60 | CHRNB2 (0.33) | — | |
| SCHEMBL27818263 | 0.60 | ALDH1A1 (0.35) | — | |
| SCHEMBL12491136 | 0.60 | GABRR1 (0.39) | SLC1A2MEN1BLMKMT2A | |
| SCHEMBL12491137 | 0.60 | GABRR1 (0.39) | SLC1A2MEN1BLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1210328-A1 | FUSED PYRROLECARBOXAMIDES: A NEW CLASS OF GABA BRAIN RECEPTOR LIGANDS | NEUROGEN CORPORATION (US) | 2002-06-05 | — | — | EP | claimed |
| WO-2001016103-A1 | FUSED PYRROLECARBOXAMIDES: GABA BRAIN RECEPTOR LIGANDS | NEUROGEN CORPORATION (US) | 2001-03-08 | — | — | WO | claimed |