SCHEMBL6545854

SCHEMBL6545854

C=Cc1cc2cccc(C(=O)O)c2c(C(=O)O)c1C=C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.44
NR4A1 P22736 1/20 0.38
NR4A2 P43354 1/20 0.38
NR4A3 Q92570 1/20 0.38
CDC25B P30305 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
PTPN1 P18031 1/20 0.36
ALDH1A1 P00352 3/20 0.34
CYP1A2 P05177 3/20 0.34
KDM4E B2RXH2 2/20 0.34
GLA P06280 1/20 0.34
HPGD P15428 1/20 0.34
CYP2C19 P33261 1/20 0.34
KEAP1 Q14145 1/20 0.34
CYP2D6 P10635 2/20 0.33
CYP2C9 P11712 1/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
ALOX15 P16050 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL890497 0.80 HSD17B10 (0.51) HSD17B10NR4A1NR4A2NR4A3CDC25B
SCHEMBL6545857 0.77 MEN1 (0.58) HSD17B10NR4A1NR4A2NR4A3CDC25B
SCHEMBL1506769 0.76 HSD17B10 (0.58) HSD17B10NR4A1NR4A2NR4A3CDC25B
SCHEMBL31401742 0.74 HSD17B10 (0.55) HSD17B10NR4A1NR4A2NR4A3CDC25B
SCHEMBL1807581 0.74 HSD17B10 (0.55) HSD17B10NR4A1NR4A2NR4A3CDC25B
SCHEMBL9419991 0.74 NR4A1 (0.41) HSD17B10NR4A1NR4A2NR4A3CDC25B
SCHEMBL8921442 0.72 HSD17B10 (0.43) HSD17B10NR4A1NR4A2NR4A3CDC25B
SCHEMBL30382166 0.72 ALDH1A1 (0.44) HSD17B10NR4A1NR4A2NR4A3CDC25B
SCHEMBL997602 0.72 ALDH1A1 (0.44) HSD17B10NR4A1NR4A2NR4A3ALDH1A1
SCHEMBL674718 0.72 ALDH1A1 (0.44) HSD17B10NR4A1NR4A2NR4A3CDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3162869-B1 CROSSLINKED RUBBER MATERIAL FOR LIQUEFIED GAS SEAL ZEON CORP (JP) 2019-06-19 EP disclosed
US-10266682-B2 Cross-linked rubber for liquefied gas seal ZEON CORPORATION (JP) 2019-04-23 US disclosed
US-20170152375-A1 CROSS-LINKED RUBBER FOR LIQUEFIED GAS SEAL ZEON CORPORATION (JP) 2017-06-01 US disclosed
EP-3162869-A1 CROSSLINKED RUBBER MATERIAL FOR LIQUEFIED GAS SEAL Zeon Corporation (JP) 2017-05-03 EP disclosed
US-6762107-B2 Capacitor and manufacturing method thereof MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2004-07-13 US disclosed
EP-1383146-A1 CAPACITOR AND ITS MANUFACTURING METHOD MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2004-01-21 EP disclosed
US-20030139016-A1 Capacitor and manufacturing method MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2003-07-24 US disclosed