Ethylbenzene

Ethylbenzene

SCHEMBL9864115

CCc1cccc(CC)c1CC.CCc1ccccc1

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.64
GABRA1 P14867 2/20 0.44
GABRB2 P47870 2/20 0.44
ALDH1A1 P00352 2/20 0.40
HTT P42858 1/20 0.40
LOXL2 Q9Y4K0 1/20 0.39
PPARG P37231 1/20 0.39
PPARA Q07869 1/20 0.39
RAB9A P51151 2/20 0.38
MAPT P10636 1/20 0.38
STAT1 P42224 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
POLB P06746 1/20 0.38
ATM Q13315 1/20 0.38
ALOX12 P18054 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HTR1A P08908 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylbenzene SCHEMBL27524247 0.98 TP53 (0.61) TP53GABRA1GABRB2ALDH1A1HTT
SCHEMBL6546008 0.87 TP53 (0.46) TP53GABRA1GABRB2ALDH1A1ALOX12
SCHEMBL9000240 0.85 GABRA1 (0.52) TP53GABRA1GABRB2MAPTNPSR1
Ethylbenzene SCHEMBL3227891 0.85 TP53 (0.78) TP53GABRA1GABRB2ALDH1A1PPARG
Ethylbenzene SCHEMBL27633722 0.85 TP53 (0.78) TP53GABRA1GABRB2ALDH1A1PPARG
Ethylbenzene SCHEMBL11185461 0.85 TP53 (0.78) TP53GABRA1GABRB2ALDH1A1PPARG
SCHEMBL245773 0.85 GABRA1 (0.57) TP53GABRA1GABRB2MAPTNPSR1
SCHEMBL6548127 0.85 HTT (0.51) TP53GABRA1GABRB2ALDH1A1HTT
SCHEMBL19644252 0.84 GABRA1 (0.46) TP53GABRA1GABRB2ALDH1A1RAB9A
SCHEMBL11203713 0.84 HTR2A (0.46) TP53GABRA1GABRB2ALDH1A1ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1019007-B MANUFACTURE OF ALKYLBENZENES LUMMUS CREST INC (US) 1992-11-11 CN disclosed
US-5003119-A Alkylation of benzene in the presence of a zeolite catalyst LUMMUS CREST, INC. (US) 1991-03-26 US disclosed
CN-1037699-A The manufacturing of alkylbenzene LUMMUS CREST INC (US) 1989-12-06 CN disclosed