Acetamide

Acetamide

SCHEMBL6546136

CC(N)=O.CN(C)C(=O)N(C)C

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.57
PMP22 Q01453 2/20 0.57
ALOX15 P16050 1/20 0.57
BLM P54132 1/20 0.57
ALDH1A1 P00352 3/20 0.39
TSHR P16473 3/20 0.39
TDP1 Q9NUW8 2/20 0.37
THPO P40225 2/20 0.35
NFKB1 P19838 1/20 0.35
HSD17B10 Q99714 1/20 0.35
MAPT P10636 1/20 0.35
APEX1 P27695 1/20 0.35
OR51E2 Q9H255 1/20 0.33
CRBN Q96SW2 1/20 0.33
ACHE P22303 1/20 0.31
FFAR3 O14843 1/20 0.31
LCK P06239 1/20 0.31
FYN P06241 1/20 0.31
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15303893 0.86 ALDH1A1 (0.39) LMNAPMP22ALOX15BLMALDH1A1
SCHEMBL6523333 0.84 ALDH1A1 (0.50) LMNAPMP22ALDH1A1TSHRTHPO
SCHEMBL24760 0.84
Thiourea SCHEMBL11357756 0.83 TSHR (0.40) LMNAPMP22ALOX15BLMALDH1A1
Acetamide SCHEMBL25171190 0.81 LMNA (0.61) LMNAPMP22ALOX15BLMALDH1A1
SCHEMBL5317417 0.81 TSHR (0.41) LMNAPMP22ALOX15BLMALDH1A1
Acetic Acid SCHEMBL27795666 0.81 FFAR3 (0.54) LMNAPMP22ALOX15BLMALDH1A1
Hydrochloric Acid SCHEMBL31267456 0.81 ALDH1A1 (0.47) LMNAPMP22ALDH1A1TSHRTHPO
SCHEMBL31004029 0.81
Bromide SCHEMBL29640683 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1074587-B1 Gamma quinacridone pigment CIBA SC HOLDING AG (CH) 2004-01-14 EP claimed