SCHEMBL6546273

SCHEMBL6546273

O=C(Cl)Oc1c2ccccc2cc2ccccc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.48
HPGD P15428 4/20 0.48
KDM4E B2RXH2 3/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
HSD17B10 Q99714 2/20 0.48
CYP1A2 P05177 1/20 0.48
GLA P06280 1/20 0.48
CYP2C19 P33261 1/20 0.48
GPR84 Q9NQS5 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.41
NPSR1 Q6W5P4 1/20 0.40
ERN1 O75460 1/20 0.40
GAA P10253 1/20 0.39
CYP3A4 P08684 1/20 0.38
TUBB4A P04350 1/20 0.38
TUBB P07437 1/20 0.38
TUBA3C P0DPH7 1/20 0.38
TUBA1B P68363 1/20 0.38
TUBA4A P68366 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8060132 0.83 ALDH1A1 (0.52) ALDH1A1HPGDKDM4EMEN1KMT2A
SCHEMBL3999298 0.82 ALDH1A1 (0.55) ALDH1A1HPGDKDM4EMEN1KMT2A
SCHEMBL4752091 0.80 KDM4E (0.54) ALDH1A1HPGDKDM4EMEN1KMT2A
SCHEMBL28059710 0.80 KMT2A (0.48) ALDH1A1HPGDKDM4EMEN1KMT2A
SCHEMBL7197218 0.79 NCEH1 (0.46) ALDH1A1HPGDHSD17B10CYP1A2CYP2C19
SCHEMBL11867995 0.78 TSHR (0.46) ALDH1A1HPGDKDM4EKMT2AHSD17B10
SCHEMBL23271769 0.77 HSD17B10 (0.49) ALDH1A1HPGDKDM4EMEN1KMT2A
Hydrochloric Acid SCHEMBL7459859 0.77 POLB (0.50) ALDH1A1HPGDKDM4EMEN1KMT2A
SCHEMBL12133797 0.77 KMT2A (0.56) ALDH1A1HPGDKDM4EMEN1KMT2A
SCHEMBL6604158 0.76 ALDH1A1 (0.60) ALDH1A1HPGDKDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1301509-B1 MULTIFUNCTIONAL COUPLING AGENTS WITH CYCLIC IMINOESTER AND IMINOETHER GROUPS, METHOD FOR PRODUCING THE SAME AND USE THEREOF INST POLYMERFORSCHUNG DRESDEN (DE) 2004-10-06 EP disclosed
EP-1257265-B1 USE OF 2-PHENYLENE DIAMINE DERIVATIVES FOR THE TREATMENT OF INFECTIONS BIOAGENCY AG (DE) 2004-01-21 EP disclosed
EP-1301509-A1 MULTIFUNCTIONAL COUPLING AGENTS WITH CYCLIC IMINOESTER AND IMINOETHER GROUPS, METHOD FOR PRODUCING THE SAME AND USE THEREOF Institut für Polymerforschung Dresden E.V. (DE) 2003-04-16 EP disclosed
EP-1257265-A2 USE OF 2-PHENYLENE DIAMINE DERIVATIVES FOR THE TREATMENT OF INFECTIONS Jomaa Pharmaka GmbH (DE) 2002-11-20 EP disclosed
WO-2002004441-A1 MULTIFUNCTIONAL COUPLING AGENTS WITH CYCLIC IMINOESTER AND IMINOETHER GROUPS, METHOD FOR PRODUCING THE SAME AND USE THEREOF INSTITUT FÜR POLYMERFORSCHUNG DRESDEN E.V. (DE) 2002-01-17 WO disclosed
WO-2001062709-A2 USE OF 2-PHENYLENE DIAMINE DERIVATIVES FOR THE TREATMENT OF INFECTIONS JOMAA PHARMAKA GMBH (DE) 2001-08-30 WO disclosed
EP-0624594-B1 Monomeric bile acid derivatives, a process for their production, and their use as medicines HOECHST AG (DE) 1999-08-11 EP disclosed
EP-0624594-A2 Monomeric bile acid derivatives, a process for their production, and their use as medicines HOECHST AKTIENGESELLSCHAFT (DE) 1994-11-17 EP disclosed
EP-0062611-B1 PHOTOPOLYMERISATION PROCESS CIBA-GEIGY AG (CH) 1985-04-24 EP disclosed
EP-0062611-A2 Photopolymerisation process CIBA-GEIGY AG (CH) 1982-10-13 EP disclosed