Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8060132 | 0.83 | ALDH1A1 (0.52) | KMT2AKDM4EALDH1A1MEN1HPGD | |
| SCHEMBL3999298 | 0.82 | ALDH1A1 (0.55) | KMT2AKDM4EALDH1A1MEN1HPGD | |
| SCHEMBL8782836 | 0.81 | ERN1 (0.43) | KMT2AKDM4EALDH1A1MEN1HPGD | |
| SCHEMBL4752091 | 0.80 | KDM4E (0.54) | KMT2AKDM4EALDH1A1MEN1HPGD | |
| SCHEMBL6546273 | 0.80 | ALDH1A1 (0.48) | KMT2AKDM4EALDH1A1MEN1HPGD | |
| SCHEMBL29728547 | 0.79 | NCEH1 (0.47) | KDM4EALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL6929061 | 0.78 | TSHR (0.46) | KMT2AKDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL23271769 | 0.77 | HSD17B10 (0.49) | KMT2AKDM4EALDH1A1MEN1HPGD | |
| SCHEMBL12133797 | 0.77 | KMT2A (0.56) | KMT2AKDM4EALDH1A1MEN1HPGD | |
| SCHEMBL6511350 | 0.77 | ALDH1A1 (0.42) | KMT2AKDM4EALDH1A1MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119269811-A | Neuroactive steroids, compositions, and uses thereof | 萨奇治疗股份有限公司 | 2025-01-07 | — | — | CN | disclosed |
| CN-119192267-A | Neuroactive steroids, compositions, and uses thereof | 萨奇治疗股份有限公司 | 2024-12-27 | — | — | CN | disclosed |
| CN-110105434-B | Stapled and stitched polypeptides and uses thereof | 哈佛大学的校长及成员们 | 2024-09-17 | — | — | CN | disclosed |
| CN-113956315-B | Neuroactive steroids, compositions, and uses thereof | 萨奇治疗股份有限公司 | 2024-08-09 | — | — | CN | disclosed |
| CN-118059096-A | Methods of treating CNS disorders | 杭州高光制药有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-116490180-B | Methods of treating CNS disorders | 杭州高光制药有限公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-114615999-B | Drug antibody conjugates | 法马马有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-117642404-A | Small molecule modulators of glucocerebrosidase activity and uses thereof | 凡况生化公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-115885042-A | Double-stranded oligonucleotide compositions and methods related thereto | 波涛生命科学有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-107427521-B | Inhibitors of cyclin dependent kinases | 达纳-法伯癌症研究所股份有限公司 | 2021-08-03 | — | — | CN | disclosed |
| CN-110520117-A | Substituted eutectic of glycine compound and application thereof | SYNEURX INT TAIWAN CORP | 2019-11-29 | — | — | CN | disclosed |
| CN-109563018-A | Eutectic of sodium benzoate and application thereof | 心悦生医股份有限公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-109563024-A | Eutectic of lithium benzoate and use thereof | 心悦生医股份有限公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-109069508-A | EZH2 inhibitor and application thereof | 达纳-法伯癌症研究所股份有限公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-108349924-A | Benzenesulfonamido--benzofuran derivatives and application thereof | 纪念斯隆凯特林癌症中心 | 2018-07-31 | — | — | CN | disclosed |
| CN-105377808-B | Method for producing trans-bis (aminomethyl) cyclohexane and method for producing bis (isocyanatomethyl) cyclohexane | 三井化学株式会社 | 2018-05-29 | — | — | CN | disclosed |
| CN-107417616-A | Methods and compositions for treating beta-thalassemia and sickle cell disease | 中央研究院 | 2017-12-01 | — | — | CN | disclosed |
| CN-107105651-A | Ezh2 inhibitor and application thereof | 达纳-法伯癌症研究所股份有限公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-105492428-A | Methods and compositions for treating beta-thalassemia and sickle cell disease | ACADEMIA SINICA | 2016-04-13 | — | — | CN | disclosed |