Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.77 |
| ▸ | MAPT | P10636 | 3/20 | 0.77 |
| ▸ | PKM | P14618 | 2/20 | 0.77 |
| ▸ | MMP1 | P03956 | 4/20 | 0.70 |
| ▸ | MMP2 | P08253 | 4/20 | 0.70 |
| ▸ | MMP9 | P14780 | 4/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.64 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 4/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9314178 | 1.00 | KDM4E (0.77) | KDM4EMAPTPKMMMP1MMP2 | |
| SCHEMBL5176156 | 1.00 | KDM4E (0.77) | KDM4EMAPTPKMMMP1MMP2 | |
| SCHEMBL5177416 | 1.00 | KDM4E (0.77) | KDM4EMAPTPKMMMP1MMP2 | |
| SCHEMBL7771097 | 0.92 | MMP1 (0.73) | KDM4EMAPTPKMMMP1MMP2 | |
| SCHEMBL7771073 | 0.92 | MMP1 (0.73) | KDM4EMAPTPKMMMP1MMP2 | |
| SCHEMBL11140030 | 0.88 | KDM4E (0.81) | KDM4EMAPTPKMALDH1A1HPGD | |
| SCHEMBL11140025 | 0.88 | KDM4E (0.81) | KDM4EMAPTPKMALDH1A1HPGD | |
| SCHEMBL5176155 | 0.85 | MMP1 (0.65) | KDM4EMAPTPKMMMP1MMP2 | |
| SCHEMBL5177059 | 0.85 | MMP1 (0.65) | KDM4EMAPTPKMMMP1MMP2 | |
| SCHEMBL5176144 | 0.85 | MMP1 (0.65) | KDM4EMAPTPKMMMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023180189-A1 | MPRO TARGETING ANTIVIRAL COMPOUNDS | EXSCIENTIA AI LIMITED (GB) | 2023-09-28 | — | — | WO | disclosed |
| EP-2686306-B1 | BENZO[B][1,4]OXAZIN DERIVATIVES AS CALCIUM SENSING RECEPTOR MODULATORS | LUPIN ATLANTIS HOLDINGS SA (CH) | 2017-01-04 | — | — | EP | disclosed |
| US-9464063-B2 | Benzo [B] [1,4] oxazin derivatives as calcium sensing receptor modulators | LUPIN ATLANTIS HOLDINGS SA (CH) | 2016-10-11 | — | — | US | disclosed |
| US-20140018358-A1 | BENZO [B] [1,4] OXAZIN DERIVATIVES AS CALCIUM SENSING RECEPTOR MODULATORS | LUPIN LIMITED (IN) | 2014-01-16 | — | — | US | disclosed |
| US-20040110256-A1 | Method of decomposing unsaturated carboxylic acid copolymer | IDEMITSU KOSAN CO. LTD. (JP) | 2004-06-10 | — | — | US | disclosed |
| EP-1382671-A1 | METHOD OF DECOMPOSING UNSATURATED CARBOXYLIC ACID COPOLYMER | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2004-01-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140018358-A1 | BENZO [B] [1,4] OXAZIN DERIVATIVES AS CALCIUM SENSING RECEPTOR MODULATORS | CASR, RYR1, RYR2 | KDM4E 4297/4885MAPT 2509/4885PKM 1437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.