SCHEMBL5176155

SCHEMBL5176155

NC(=O)C=CC(=O)Nc1ccccc1O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 4/20 0.65
MMP2 P08253 4/20 0.65
MMP9 P14780 4/20 0.65
ALDH1A1 P00352 6/20 0.64
MAPT P10636 5/20 0.64
HTT P42858 4/20 0.64
GAA P10253 3/20 0.64
LMNA P02545 3/20 0.59
MCL1 Q07820 1/20 0.59
PKM P14618 2/20 0.56
NLRP1 Q9C000 1/20 0.56
KDM4E B2RXH2 3/20 0.56
HPGD P15428 2/20 0.54
KMT2A Q03164 3/20 0.50
KDM1A O60341 2/20 0.50
NPC1 O15118 2/20 0.50
TDP1 Q9NUW8 1/20 0.50
TP53 P04637 1/20 0.50
DDAH1 O94760 1/20 0.50
MEN1 O00255 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5176144 1.00 MMP1 (0.65) MMP1MMP2MMP9ALDH1A1MAPT
SCHEMBL5177059 1.00 MMP1 (0.65) MMP1MMP2MMP9ALDH1A1MAPT
SCHEMBL7771097 0.92 MMP1 (0.73) MMP1MMP2MMP9ALDH1A1MAPT
SCHEMBL7771073 0.92 MMP1 (0.73) MMP1MMP2MMP9ALDH1A1MAPT
SCHEMBL5086029 0.90 ALDH1A1 (0.70) MMP1MMP2MMP9ALDH1A1MAPT
SCHEMBL6546458 0.85 KDM4E (0.77) MMP1MMP2MMP9ALDH1A1MAPT
SCHEMBL9314178 0.85 KDM4E (0.77) MMP1MMP2MMP9ALDH1A1MAPT
SCHEMBL5176156 0.85 KDM4E (0.77) MMP1MMP2MMP9ALDH1A1MAPT
SCHEMBL5177416 0.85 KDM4E (0.77) MMP1MMP2MMP9ALDH1A1MAPT
SCHEMBL8397639 0.82 MMP1 (0.61) MMP1MMP2MMP9ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1281516-B1 Planographic printing plate precursor FUJIFILM CORP (JP) 2007-12-19 EP disclosed
EP-1602481-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2007-05-30 EP disclosed
EP-1203659-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2006-05-17 EP disclosed
EP-1602481-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2005-12-07 EP disclosed
US-6951171-B2 Using graft polymer on etched or anodized aluminum substrate FUJI PHOTO FILM CO., LTD. (JP) 2005-10-04 US disclosed
EP-1371500-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2005-09-28 EP disclosed
US-6939658-B2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2005-09-06 US disclosed
EP-1048457-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2004-12-15 EP disclosed
US-6824946-B2 SUPPORT WITH HYDROPHILIC SURFACE HAVING AN IMAGE-FORMING LAYER CONTAINING A HYDROPHOBIC HIGH MOLECULAR COMPOUND WITH SALTS OF SULFONATES AND CARBOXYLS WITH IODONIUM, SULFONIUM OR DIAZONIUM IONS FUJI PHOTO FILM CO., LTD. (JP) 2004-11-30 US disclosed
EP-1031414-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2004-06-16 EP disclosed
US-6509132-B1 Comprises an ink-receptive image area for receiving ink during the printing process and a hydrophilic non-image area for receiving fountain solution FUJI PHOTO FILM CO., LTD. (JP) 2003-01-21 US disclosed
US-6455224-B1 SUPPORT WITH HYDROPHILIC SURFACE AND PHOTOSENSITIVE LAYER CONTAINING INFRARED ABSORBENT WHICH CHANGES FROM HYDROPHILIC TO HYDROPHOBIC BY HEAT AND HYDROPHILIC POLYMER HAVING FUNCTIONAL GROUP RENDERING LAYER WATER DEVELOPABLE FUJI PHOTO FILM CO., LTD. (JP) 2002-09-24 US disclosed
US-20020068241-A1 Lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2002-06-06 US disclosed
EP-1203659-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2002-05-08 EP disclosed
US-6379863-B1 LAMINATING HYDROPHOBIC POLYMER ON SUBSTRATE; HEATING TO MAKE HYDROPHILIC; DURABILITY; REDUCED BLEMISHES; STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 2002-04-30 US disclosed
EP-1136281-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2001-09-26 EP disclosed
US-6153352-A OBTAINED BY LAMINATING ON A SUBSTRATE A LAYER OF HYDROPHOBIC POLYMER AND A LAYER OF HYDROPHILIC POLYMER FUJI PHOTO FILM CO., LTD. (JP) 2000-11-28 US disclosed
EP-1048457-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2000-11-02 EP disclosed
EP-1031414-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2000-08-30 EP disclosed
EP-0922570-A2 Planographic printing plate precursor and a method for producing a planographic plate Fuji Photo Film Co., Ltd. (JP) 1999-06-16 EP disclosed