Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1824047 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2GAAPOLBCRHBPNPBWR1 | |
| SCHEMBL6548096 | 0.81 | HTT (0.44) | SMN1; SMN2GAAGPR52KMT2AMEN1 | |
| SCHEMBL21473089 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2GAAGPR52CRHBPNPBWR1 | |
| SCHEMBL3468225 | 0.79 | SMN1; SMN2 (0.51) | SMN1; SMN2GAAPOLBCRHBPNPBWR1 | |
| SCHEMBL7714807 | 0.77 | SMN1; SMN2 (0.43) | SMN1; SMN2GAAGPR52POLBCRHBP | |
| SCHEMBL22030308 | 0.77 | MAOA (0.42) | GAAMAOAMAOBHPGDKMT2A | |
| SCHEMBL11829374 | 0.76 | ESR1 (0.41) | SMN1; SMN2MAOAMAOBHPGDKMT2A | |
| SCHEMBL6546473 | 0.74 | NPC1 (0.51) | SMN1; SMN2GAAPOLBKMT2AMEN1 | |
| SCHEMBL6546320 | 0.73 | HTT (0.45) | SMN1; SMN2GAALMNAAKR1B1TDP1 | |
| SCHEMBL6547552 | 0.73 | GABRA1 (0.41) | POLBMAOAHPGDTRPA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717098-B1 | A refrigerating machine oil and a fluid composition for use in a refrigerating machine | NIPPON MITSUBISHI OIL CORP (JP) | 2004-01-21 | — | — | EP | disclosed |
| US-5817251-A | AROMATIC HYDROCARBON LUBRICANT | NIPPON OIL CO., LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| US-5711895-A | Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group | NIPPON OIL CO., LTD. (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0717098-A2 | A refrigerating machine oil and a fluid composition for use in a refrigerating machine | NIPPON OIL CO. LTD. (JP) | 1996-06-19 | — | — | EP | disclosed |