SCHEMBL6547004

SCHEMBL6547004

CCC(c1ccccc1C)c1ccccc1C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.50
CYP2D6 P10635 2/20 0.44
SLC6A2 P23975 2/20 0.44
SLC6A4 P31645 2/20 0.44
SLC6A3 Q01959 2/20 0.44
SLC22A2 O15244 1/20 0.44
SLC22A1 O15245 1/20 0.44
GRIN2D O15399 1/20 0.44
GRIN3B O60391 1/20 0.44
CHRM2 P08172 1/20 0.44
CHRM4 P08173 1/20 0.44
CHRM5 P08912 1/20 0.44
ADRA2A P08913 1/20 0.44
CHRM1 P11229 1/20 0.44
ADRA2B P18089 1/20 0.44
CHRM3 P20309 1/20 0.44
DRD1 P21728 1/20 0.44
HRH2 P25021 1/20 0.44
HTR2A P28223 1/20 0.44
HTR2C P28335 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL6000450 0.98 ESR1 (0.48) ESR1CYP2D6SLC6A2SLC6A4SLC6A3
SCHEMBL2350960 0.91 HTR2A (0.50) ESR1CYP2D6SLC6A2SLC6A4SLC6A3
Diethylamine SCHEMBL8172450 0.89 ESR1 (0.42) ESR1CYP2D6SLC6A2SLC6A4SLC6A3
SCHEMBL6546231 0.89 ESR1 (0.42) ESR1CYP2D6SLC6A2SLC6A4SLC6A3
SCHEMBL6546848 0.88 ESR1 (0.41) ESR1CYP2D6SLC6A2SLC6A4SLC6A3
SCHEMBL6547345 0.86 ESR1 (0.39) ESR1CYP2D6SLC6A2SLC6A4SLC6A3
Benzylamine SCHEMBL10781356 0.86 LOXL2 (0.52) ESR1CYP2D6SLC6A2SLC6A4SLC6A3
SCHEMBL31538069 0.85 ESR1 (0.50) ESR1CYP2D6SLC6A2SLC6A4SLC6A3
SCHEMBL9656285 0.85 ESR1 (0.50) ESR1CYP2D6SLC6A2SLC6A4SLC6A3
SCHEMBL10781443 0.84 MEN1 (0.45) CHRM2DRD3ADRB2GAATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4777301-A CONTACTING WITH NON-ZEOLITIC MOLECULAR SIEVE UNION CARBIDE CORPORATION (US) 1988-10-11 US claimed
EP-0251169-A1 Process for the condensation of carbonyl and aromatic compounds UNION CARBIDE CORPORATION (US) 1988-01-07 EP claimed
CN-116802187-A Organometallic compounds 优米科尔股份公司及两合公司 2023-09-22 CN disclosed
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-6204259-B1 Manganese complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide MONSANTO COMPANY 2001-03-20 US disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed
US-5073176-A Permselective E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-12-17 US disclosed
EP-0138741-B1 TEMPERATURE-INDICATING SHEET Matsumoto Kosan Kabushiki Kaisha (JP) 1990-11-07 EP disclosed
US-4777301-A CONTACTING WITH NON-ZEOLITIC MOLECULAR SIEVE UNION CARBIDE CORPORATION (US) 1988-10-11 US disclosed
EP-0251169-A1 Process for the condensation of carbonyl and aromatic compounds UNION CARBIDE CORPORATION (US) 1988-01-07 EP disclosed
US-4601588-A COMPONENT WHICH MELTS AT A PORESCRIBED TEMPERATURE AND CHANGES COLOR, INDICATING FRESHNESS OF FROZEN FOODS MATSUMOTO KOSAN KABUSHIKI KAISHA (JP) 1986-07-22 US disclosed
EP-0138741-A2 Temperature-indicating sheet Matsumoto Kosan Kabushiki Kaisha (JP) 1985-04-24 EP disclosed